(Q36371501)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT (English)

1 reference

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21 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Shigeharu Myou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Alan R Leff

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Saori Myo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Evan Boetticher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Jiankun Tong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Angelo Y Meliton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Jie Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Nilda M Munoz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

21 December 2019

published in

1 reference

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21 December 2019

volume

198

1 reference

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21 December 2019

issue

1 reference

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21 December 2019

page(s)

1573-1582

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma

21 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

In vivo and in vitro effects of SAR 943, a rapamycin analogue, on airway inflammation and remodeling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

In vivo protein transduction: delivery of a biologically active protein into the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin 5: the role of specific adhesion molecules and phosphatidylinositol 3-kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperreactivity in sensitized guinea pigs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

PI 3-kinase: structural and functional analysis of intersubunit interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Immunological aspects of allergic asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

In vivo priming of FcalphaR functioning on eosinophils of allergic asthmatics.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

IL-5-induced integrin adhesion of human eosinophils caused by ERK1/2-mediated activation of cPLA2.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Blockade of focal clustering and active conformation in beta 2-integrin-mediated adhesion of eosinophils to intercellular adhesion molecule-1 caused by transduction of HIV TAT-dominant negative Ras.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Effect of wortmannin on human eosinophil responses in vitro and on bronchial inflammation and airway hyperresponsiveness in Guinea pigs in vivo

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

Expression and activation of protein kinase C-zeta in eosinophils after allergen challenge.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells

21 September 2018

1 reference

12 December 2020

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

1 reference

12 December 2020

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

1 reference

12 December 2020

Il-13 and IFN-gamma: interactions in lung inflammation

1 reference

12 December 2020

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

12 December 2020

Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man

1 reference

12 December 2020

Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression

1 reference

12 December 2020

Contraction of human bronchial smooth muscle caused by activated human eosinophils

1 reference

12 December 2020

Effects of an antibody to interleukin-5 in a monkey model of asthma

1 reference

12 December 2020

Mechanisms of smooth muscle contraction elicited by cationic proteins in guinea pig trachealis

1 reference

12 December 2020

Cellular protein kinase C activity in asthma

1 reference

12 December 2020

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

12 December 2020

Signaling in neuropeptide-induced migration of human eosinophils

1 reference

12 December 2020

TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma

1 reference

12 December 2020

Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells

1 reference

12 December 2020

IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals

1 reference

12 December 2020

Bronchoconstrictor effects of leukotriene C in humans

1 reference

12 December 2020

Bronchial responsiveness among inbred mouse strains. Role of airway smooth-muscle shortening velocity

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20030298

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

14623911

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json