(Q34831355)

4 August 2017

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title

Signalling, cell cycle and pluripotency in embryonic stem cells (English)

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4 August 2017

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Tom Burdon

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4 August 2017

Austin Smith

series ordinal

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4 August 2017

Pierre Savatier

series ordinal

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4 August 2017

language of work or name

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1 September 2002

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4 August 2017

published in

Trends in Cell Biology

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4 August 2017

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4 August 2017

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4 August 2017

page(s)

432-438

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Introducing embryonic stem cells

4 August 2017

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7 January 2021

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

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7 January 2021

Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage

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Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

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LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

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7 January 2021

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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7 January 2021

The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3

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Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells

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7 January 2021

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

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7 January 2021

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

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7 January 2021

Gab-family adapter molecules in signal transduction of cytokine and growth factor receptors, and T and B cell antigen receptors

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7 January 2021

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

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7 January 2021

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

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7 January 2021

Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation.

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7 January 2021

Shp-2 has a positive regulatory role in ES cell differentiation and proliferation

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7 January 2021

Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells.

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7 January 2021

The PI3K-PDK1 connection: more than just a road to PKB

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7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

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7 January 2021

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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7 January 2021

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

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7 January 2021

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

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7 January 2021

Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein

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7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

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7 January 2021

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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7 January 2021

Pathways governing G1/S transition and their response to DNA damage

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7 January 2021

Aberrations of the G1- and G1/S-regulating genes in human cancer

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7 January 2021

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7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

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7 January 2021

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

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7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

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7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

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7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

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7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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7 January 2021

E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)

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7 January 2021

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

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7 January 2021

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

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7 January 2021

p53-independent DNA repair and cell cycle arrest in embryonic stem cells

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7 January 2021

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7 January 2021

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7 January 2021

G1-phase regulators, cyclin D1, cyclin D2, and cyclin D3: up-regulation at gastrulation and dynamic expression during neurulation

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7 January 2021

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

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7 January 2021

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

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7 January 2021

Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells

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7 January 2021

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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7 January 2021

Dependence of cyclin E-CDK2 kinase activity on cell anchorage.

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7 January 2021

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

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7 January 2021

Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.

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7 January 2021

pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation

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7 January 2021

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

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7 January 2021

Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6

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7 January 2021

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

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7 January 2021

Isolation of a primate embryonic stem cell line

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7 January 2021

Derivation of pluripotent stem cells from cultured human primordial germ cells

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7 January 2021

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

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7 January 2021

10.1016/S0962-8924(02)02352-8

Identifiers

DOI

1 reference

4 August 2017

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