(Q42815554)

7 November 2017

title

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts (English)

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7 November 2017

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Brown JP

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7 November 2017

Wei W

series ordinal

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7 November 2017

Sedivy JM

series ordinal

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7 November 2017

language of work or name

English

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publication date

1 August 1997

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7 November 2017

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7 November 2017

volume

277

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7 November 2017

issue

5327

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7 November 2017

page(s)

831-834

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describes a project that uses

7 November 2017

LF1

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cites work

The serial cultivation of human diploid cell strains

2 references

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/0014-4827(61)90192-6

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Differential CDK-inhibitor gene expression in aging human diploid fibroblasts

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Induction of cellular senescence in immortalized cells by human chromosome 1.

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Replicative senescence: the human fibroblast comes of age.

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24 May 2022

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Telomeres shorten during ageing of human fibroblasts

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24 May 2022

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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24 May 2022

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Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Replicative senescence of human fibroblast-like cells in culture

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24 May 2022

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Telomerase, Cell Immortality, and Cancer

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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Analysis of biological selections for high-efficiency gene targeting

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Mechanisms involved in the immortalization of mammalian cells by ionizing radiation and chemical carcinogens.

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Increased p53 Protein Associated with Aging in Human Diploid Fibroblasts

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.277.5327.831

Identifiers

DOI

10.1126/SCIENCE.277.5327.831

1 reference

7 November 2017

1 reference