(Q34706597)

English

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Huntington's disease

0 references

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

object named as

Kevin R Jones

11

1 reference

ORCID Public Data File 2021

7

object named as

M Flint Beal

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

author name string

Andrew D Strand

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

Zachary C Baquet

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

Aaron K Aragaki

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

Lichuan Yang

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

Lesley Jones

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

James M Olson

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

Charles Kooperberg

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

language of work or name

0 references

publication date

1 October 2007

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

27

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

43

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

11758-11768

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

describes a project that uses

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/6673215

based on heuristic

inferred from PubMed Central ID database lookup

Gene ontology: tool for the unification of biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins: roles in neuronal development and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse models of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional and progressive thinning of the cortical ribbon in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic rat model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF and activity-dependent synaptic modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On parametric empirical Bayes methods for comparing multiple groups using replicated gene expression profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The energetics of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioconductor: open software development for computational biology and bioinformatics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal evolution of mouse striatal gene expression following MPTP injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MPTP model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional cortical thinning in preclinical Huntington disease and its relationship to cognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juvenile Huntington's disease: does a dosage-effect pathogenic mechanism differ from the classical adult disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knock-in mouse models of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional and cellular gene expression changes in human Huntington's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of brain-derived neurotrophic factor in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conservation of regional gene expression in mouse and human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological classification of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postnatal development of excitatory synaptic input to the rat neostriatum: an electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17959817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2461-07.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673215&resulttype=core&format=json

16 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34706597&oldid=1971229727"