(Q24294798)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0050873

PPARG coactivator 1 alpha

GOA release 2020-03-11

1 reference

Peroxisome proliferator activated receptor gamma

GOA release 2020-03-11

1 reference

UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue

GOA release 2020-03-11

0 references

Bruce M Spiegelman

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language of work or name

English

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publication date

February 2003

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78-90

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cites work

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Role of the beta(3)-adrenergic receptor and/or a putative beta(4)-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-gamma coactivator-1.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Thyroid hormone regulation of mitochondrial function. Comments on the mechanism of signal transduction

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Whole-body energy metabolism and skeletal muscle biochemical characteristics

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a beta(3)-adrenergic agonist and lack of effect of leptin

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Multiple signals converging on NF-kappaB.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

A CTD function linking transcription to splicing

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

PPAR gamma is required for placental, cardiac, and adipose tissue development

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

A role for brown adipose tissue in diet-induced thermogenesis

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Towards a molecular understanding of adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Thyroid hormone and other regulators of uncoupling proteins

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Activation of the nuclear receptor peroxisome proliferator-activated receptor gamma promotes brown adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

PGC-1 functions as a transcriptional coactivator for the retinoid X receptors

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Energy metabolism in uncoupling protein 3 gene knockout mice

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Molecular biology of brown adipose tissue

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Thyroid hormone control of thermogenesis and energy balance

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Genetic studies of brown adipocyte induction

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Transcription units as RNA processing units

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Histone acetylation and transcriptional regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Brown adipose tissue. More than an effector of thermogenesis?

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV.

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Activation of PPARgamma coactivator-1 through transcription factor docking

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gamma

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Transcriptional coactivator complexes

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

Skeletal muscle metabolism is a major determinant of resting energy expenditure

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

https://api.crossref.org/works/10.1210%2FER.2002-0012

7 January 2021