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Tumor necrosis factor signaling.
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1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Tumor necrosis factor signaling
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author
Harald Wajant
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Klaus Pfizenmaier
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2
object named as
Pfizenmaier K
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Peter Scheurich
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3
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Scheurich P
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
publication date
1 January 2003
1 reference
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Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
45-65
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
cites work
A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human pro-tumor necrosis factor is a homotrimer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emerging families of cytokines and receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TNF and TNF receptor superfamilies: integrating mammalian biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modularity in the TNF-receptor family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-tumor necrosis factor therapies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel domain within the 55 kd TNF receptor signals cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis signaling by death receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine regulation of secondary lymphoid organ development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of tumor necrosis factor-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor receptor p55-deficient mice respond to acute Yersinia enterocolitica infection with less apoptosis and more effective host resistance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane‐bound TNF in experimental cerebral malaria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exacerbation of Mycobacterium tuberculosis enteritis masquerading as Crohn's disease after treatment with a tumor necrosis factor-alpha inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolated limb perfusion for extremity soft-tissue sarcomas, in-transit metastases, and other unresectable tumors: credits, debits, and future perspectives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by tumor necrosis factor and its relatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rel/NF-kappa B family: friend and foe.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NEMO/IKK gamma-deficient mice model incontinentia pigmenti.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limb and skin abnormalities in mice lacking IKKalpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKK1-deficient mice exhibit abnormal development of skin and skeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NAK is an IkappaB kinase-activating kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The essential role of MEKK3 in TNF-induced NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of receptor-interacting protein in tumor necrosis factor-alpha -dependent MEKK1 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of IkappaB kinase beta by protein kinase C isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of phosphatidylinositol 3-kinase and Rac in the nuclear signaling by tumor necrosis factor-alpha in rat-2 fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A20 inhibits NF-kappa B activation downstream of multiple Map3 kinases and interacts with the I kappa B signalosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AP-1 as a regulator of cell life and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian MAP kinase signalling cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of early-immediate genes by tumer necrosis factor alpha contribute to liver repair following chemical-induced hepatotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ASK1 is essential for JNK/SAPK activation by TRAF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling by the germinal center kinase family of protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species are downstream products of TRAF-mediated signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of FAN in TNF-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of ERK1/2 and cPLA(2) by the p55 TNF receptor occurs independently of FAN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model of the microtubule-kinesin complex based on electron cryomicroscopy and X-ray crystallography
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DENN, a novel human gene differentially expressed in normal and neoplastic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Raf by ceramide-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha supports the survival of osteoclasts through the activation of Akt and ERK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pathogenesis of vasodilatory shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-8 is required for cell death induced by expanded polyglutamine repeats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular ordering of the initial signaling events of CD95.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of TRAF2 signaling by self-induced degradation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Baculoviruses and apoptosis: the good, the bad, and the ugly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two CD95 (APO-1/Fas) signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB signals induce the expression of c-FLIP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell death protease caspase-9 by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappaB by FADD, Casper, and caspase-8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of JNK activation through NF-kappaB target genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK/SAPK activity contributes to TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A kinase-independent function of Ask1 in caspase-independent cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-alpha activates at least two apoptotic signaling cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Four deaths and a funeral: from caspases to alternative mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to the cytotoxic effects of tumor necrosis factor alpha can be overcome by inhibition of a FADD/caspase-dependent signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-independent cell killing by Fas-associated protein with death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Programmed cell death induced by ceramide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of acid and neutral sphingomyelinases in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of FADD for tumor necrosis factor-induced activation of acid sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cathepsin D targeted by acid sphingomyelinase-derived ceramide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The autophagosomal-lysosomal compartment in programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p70 tumor necrosis factor receptor mediates cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TWEAK can induce cell death via endogenous TNF and TNF receptor 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JunD protects cells from p53-dependent senescence and apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PARP is important for genomic stability but dispensable in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401189
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401189
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
12655295
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655295%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
ResearchGate publication ID
10840382
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