(Q33211246)

24 July 2017

title

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway (English)

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24 July 2017

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Christian Scholz

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24 July 2017

Thomas Wieder

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24 July 2017

Lilian Stärck

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24 July 2017

Frank Essmann

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24 July 2017

Klaus Schulze-Osthoff

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24 July 2017

Bernd Dörken

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24 July 2017

Peter T Daniel

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24 July 2017

language of work or name

English

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publication date

1 March 2005

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24 July 2017

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24 July 2017

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24 July 2017

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24 July 2017

page(s)

1904-1913

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Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of caspases and down-regulation of Bcl-2 protein

24 July 2017

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Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

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Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

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More than one way to die: apoptosis, necrosis and reactive oxygen damage

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Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance

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Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

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Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

21 January 2018

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Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis

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Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis

21 January 2018

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Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells

21 January 2018

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Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

21 January 2018

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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

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Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis

21 January 2018

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Mitochondrial control of cell death

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Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

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Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability

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Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

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Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner

21 January 2018

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The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

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Mitochondrial membrane potential monitored by JC-1 dye.

21 January 2018

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Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

21 January 2018

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Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

21 January 2018

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Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors

21 January 2018

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Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.

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Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

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Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

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Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

21 January 2018

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

21 January 2018

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Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

21 January 2018

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

21 January 2018

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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

21 January 2018

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Cell death: the significance of apoptosis

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Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells

21 January 2018

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The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms

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Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations

21 January 2018

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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7 January 2021

Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

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7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

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7 January 2021

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

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7 January 2021

Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208233

1 reference

Dimensions Publication ID

24 July 2017

1004981590

0 references

1 reference