(Q34312499)

1 August 2017

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title

DNA damage-induced apoptosis (English)

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1 August 2017

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Boris Zhivotovsky

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Chris J Norbury

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1 August 2017

language of work or name

English

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publication date

1 April 2004

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

2797-2808

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Characterization of a novel proapoptotic caspase-2- and caspase-9-binding protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

A kinase-independent function of Ask1 in caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Activation of CPP32-like protease in tumor necrosis factor-induced apoptosis is dependent on mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Death and anti-death: tumour resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Activation of cyclin A-dependent protein kinases during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Cellular responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

A novel Apaf-1-independent putative caspase-2 activation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Cell nucleus and DNA fragmentation are not required for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

p53-dependent apoptosis pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Drosophila p53 preserves genomic stability by regulating cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Oxidative stress induces nuclear loss of DNA repair proteins Ku70 and Ku80 and apoptosis in pancreatic acinar AR42J cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Cell death: the significance of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Oxygen stress induces an apoptotic cell death associated with fragmentation of mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Genetic control of programmed cell death in the nematode C. elegans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Cytochrome c-mediated apoptosis in cells lacking mitochondrial DNA. Signaling pathway involving release and caspase 3 activation is conserved

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Schizosaccharomyces pombe Rad9 contains a BH3-like region and interacts with the anti-apoptotic protein Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Involvement of histone phosphorylation in thymocyte apoptosis by protein phosphatase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Ataxia telangiectasia mutated-dependent apoptosis after genotoxic stress in the developing nervous system is determined by cellular differentiation status.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Cdc2 activation is not required for thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Mitochondrial endonuclease G is important for apoptosis in C. elegans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Distinct pathways for stimulation of cytochrome c release by etoposide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Mitochondrial DNA determines the cellular response to cancer therapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

1 reference

7 January 2021

53BP1, a mediator of the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Ultraviolet radiation-induced apoptosis is mediated by Daxx

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

SLAM (CDw150) is a cellular receptor for measles virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207532

7 January 2021

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.1038/NCB950

Identifiers

DOI

10.1038/SJ.ONC.1207532

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Dimensions Publication ID

1 August 2017

1046384652

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