(Q33207923)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

main subject

transmembrane protein

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Guojun Zhao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Guozhang Mao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Jianxin Tan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Yunzhou Dong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Seong-Hun Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

13 October 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

50647-50650

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

4 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Identity and function of γ‐secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Elevated abeta42 in skeletal muscle of Alzheimer disease patients suggests peripheral alterations of AbetaPP metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400473200

21 January 2018

Identifiers

DOI

10.1074/JBC.C400473200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json

release_m6dyaxyji5aivl4d6xrux36cjm

4 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/m6dyaxyji5aivl4d6xrux36cjm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485850%20AND%20SRC:MED&resulttype=core&format=json