(Q28591685)

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The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation

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Europe PubMed Central

PubMed publication ID

21 June 2017

The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

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Huntingtin-associated protein 1

1 reference

GOA release 2020-03-11

author name string

Yvette C Wong

1

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Europe PubMed Central

PubMed publication ID

21 June 2017

Erika L F Holzbaur

2

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Europe PubMed Central

PubMed publication ID

21 June 2017

language of work or name

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publication date

1 January 2014

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Europe PubMed Central

PubMed publication ID

21 June 2017

Journal of Neuroscience

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Europe PubMed Central

PubMed publication ID

21 June 2017

34

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Europe PubMed Central

PubMed publication ID

21 June 2017

4

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Europe PubMed Central

PubMed publication ID

21 June 2017

1293-1305

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Europe PubMed Central

PubMed publication ID

21 June 2017

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3898289/fullTextXML

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dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration

1 reference

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Shaping the role of mitochondria in the pathogenesis of Huntington's disease

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Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.

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1 reference

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17 March 2017

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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17 March 2017

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Autophagosome formation: core machinery and adaptations

1 reference

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Autophagy gone awry in neurodegenerative diseases

1 reference

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1 reference

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

1 reference

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Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

1 reference

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Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

1 reference

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

1 reference

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1 reference

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1 reference

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Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.

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1 reference

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29 September 2017

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Dynein mutations impair autophagic clearance of aggregate-prone proteins

1 reference

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29 September 2017

Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

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1 reference

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1 reference

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1 reference

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27 November 2018

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1 reference

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Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898289

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Autophagy regulates the processing of amino terminal huntingtin fragments

1 reference

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27 November 2018

Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898289

27 November 2018

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898289

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Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

1 reference

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27 November 2018

Identifiers

10.1523/JNEUROSCI.1870-13.2014

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

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