(Q34626231)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

0 references

N-(phenylmethyl)-4-quinazolinamine

1 reference

ChEBI release 2020-05-28

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Stuart L Schreiber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Sara Imarisio

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Sandra Pineau

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Axelle Cordenier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Rebecca L Maglathlin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

John A Webster

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

David C Rubinsztein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

7 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

331-338

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

Potential therapeutic applications of autophagy

30 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Drosophila in the study of neurodegenerative disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Growing roles for the mTOR pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Lithium induces autophagy by inhibiting inositol monophosphatase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Autophagy defends cells against invading group A Streptococcus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Methods for monitoring autophagy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Lessons from animal models of Huntington's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Autophagy as a regulated pathway of cellular degradation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

TOR, a central controller of cell growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

A molecular investigation of true dominance in Huntington's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

PKR-dependent autophagic degradation of herpes simplex virus type 1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Rapamycin alleviates toxicity of different aggregate-prone proteins

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635561

Inhibition of Fast Axonal Transport by erythro-9-[3-(2-Hydroxynonyl)]Adenine

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17486044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

2 references

PubMed

https://pubmed.ncbi.nlm.nih.gov/17486044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO883

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO883

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

17486044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486044%20AND%20SRC:MED&resulttype=core&format=json