(Q28505110)

24 January 2017

title

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells (English)

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Polycystin 2, transient receptor potential cation channel

24 January 2017

main subject

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Polycystin 1, transient receptor potential channel interacting

GOA release 2020-03-11

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GOA release 2020-03-11

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Weining Lu

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Donald E. Ingber

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24 January 2017

Surya M. Nauli

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24 January 2017

Francis J. Alenghat

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24 January 2017

Ying Luo

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24 January 2017

Eric Williams

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24 January 2017

Peter Vassilev

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24 January 2017

Xiaogang Li

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24 January 2017

Andrew E. H. Elia

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24 January 2017

Edward M. Brown

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24 January 2017

Stephen J. Quinn

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24 January 2017

Jing Zhou

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24 January 2017

language of work or name

English

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publication date

1 February 2003

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24 January 2017

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24 January 2017

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24 January 2017

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24 January 2017

page(s)

129–137

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Extrarenal manifestations of autosomal dominant polycystic kidney disease

24 January 2017

cites work

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7 January 2021

The genetics and physiology of polycystic kidney disease

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7 January 2021

Polycystin channels and kidney disease.

1 reference

7 January 2021

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro

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7 January 2021

Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2

1 reference

7 January 2021

Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.

1 reference

7 January 2021

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

1 reference

7 January 2021

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease

1 reference

7 January 2021

Polycystin-2 is an intracellular calcium release channel

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7 January 2021

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

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7 January 2021

Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.

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7 January 2021

Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

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7 January 2021

Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium

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7 January 2021

The propulsion of mucus by cilia

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7 January 2021

Mutant sensory cilia in the nematode Caenorhabditis elegans

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7 January 2021

Cilia propel the embryo in the right direction.

1 reference

7 January 2021

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

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7 January 2021

The ion channel polycystin-2 is required for left-right axis determination in mice

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7 January 2021

Bending the MDCK cell primary cilium increases intracellular calcium

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7 January 2021

Flow-mediated endothelial mechanotransduction

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7 January 2021

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

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7 January 2021

Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects

1 reference

7 January 2021

Discrete Distribution of binding sites for Dolichos biflorus agglutinin (DBA) and for peanut agglutinin (PNA) in mouse organ tissues

1 reference

7 January 2021

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

7 January 2021

Identification and localization of polycystin, the PKD1 gene product

1 reference

7 January 2021

Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.

1 reference

7 January 2021

Developmental changes in ryanodine- and IP(3)-sensitive Ca(2+) pools in ovine basilar artery

1 reference

7 January 2021

Protease-activated receptors: sentries for inflammation?

1 reference

7 January 2021

Molecular mechanisms of thrombin-induced endothelial cell permeability

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7 January 2021

Polycystin 1 is required for the structural integrity of blood vessels

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7 January 2021

Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene

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7 January 2021

Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant

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7 January 2021

Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes

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7 January 2021

Polycystin expression during embryonic development of human kidney in adult tissues and ADPKD tissue

1 reference

7 January 2021

Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney

1 reference

7 January 2021

The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease

1 reference

7 January 2021

The mouse homolog of PKD1: sequence analysis and alternative splicing

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7 January 2021

Molecular cloning, cDNA sequence analysis, and chromosomal localization of mouse Pkd2.

1 reference

7 January 2021

Characterization of the murine polycystic kidney disease (Pkd2) gene

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7 January 2021

Polycystin-1 expression in PKD1, early-onset PKD1, and TSC2/PKD1 cystic tissue

1 reference

7 January 2021