(Q28243157)

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Ya-Li Lee

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Christian M Beausejour

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Jeremy M Rock

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Sheldon Augustus

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Andrew C Jamieson

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Matthew H Porteus

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Michael C Holmes

In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence

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language of work or name

English

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publication date

2 June 2005

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published in

Nature

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volume

435

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issue

7042

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page(s)

646-51

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cites work

1 reference

Design and selection of novel Cys2His2 zinc finger proteins

21 April 2017

1 reference

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 April 2017

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Molecular views of recombination proteins and their control

21 April 2017

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Enhancing Gene Targeting with Designed Zinc Finger Nucleases

21 April 2017

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

21 April 2017

1 reference

Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway

21 April 2017

1 reference

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

21 April 2017

1 reference

Chimeric nucleases stimulate gene targeting in human cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Therapeutic gene targeting

21 April 2017

1 reference

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Occurrence of leukaemia following gene therapy of X-linked SCID.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

High frequency targeting of genes to specific sites in the mammalian genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

21 January 2018

1 reference

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Co-chairman's remarks: protein designs for the specific recognition of DNA.

21 January 2018

1 reference

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Advances in zinc finger engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Drug discovery with engineered zinc-finger proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

A detailed study of the substrate specificity of a chimeric restriction enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Gene conversion tracts from double-strand break repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Primary immunodeficiency diseases due to defects in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Rapid, high-throughput engineering of sequence-specific zinc finger DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Pointing fingers at the limiting step in gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556

Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity.

21 January 2018

1 reference

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Expressing the human genome

21 January 2018

1 reference

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Physical basis of a protein-DNA recognition code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03556