(Q28198051)

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Signaling through focal adhesion kinase

scientific article (publication date: 1999)

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Signaling through focal adhesion kinase (English)

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author name string

D D Schlaepfer

1

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C R Hauck

2

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D J Sieg

3

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language of work or name

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publication date

1999

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Progress in Biophysics and Molecular Biology

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71

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3-4

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435-78

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Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

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The Related Adhesion Focal Tyrosine Kinase Differentially Phosphorylates p130Cas and the Cas-like Protein, p105HEF1

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Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

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Gelsolin is a downstream effector of rac for fibroblast motility

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RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells

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p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors

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NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)

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Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase

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Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading

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Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn

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Requirement of integrin beta3 tyrosine 747 for beta3 tyrosine phosphorylation and regulation of alphavbeta3 avidity

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Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

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The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors.

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Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton

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Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

1 reference

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Casting light on focal adhesions

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Cloning of focal adhesion kinase, pp125FAK, from rat brain reveals multiple transcripts with different patterns of expression

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Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activity

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Focal adhesions, contractility, and signaling

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Focal adhesion assembly

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Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

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Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

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Prolactin stimulates the JAK2 and focal adhesion kinase pathways in human breast carcinoma T47-D cells

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

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c-Src is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase

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Geometric control of cell life and death

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Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

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Control of adhesion-dependent cell survival by focal adhesion kinase

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Signaling through focal adhesion kinase

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based on heuristic

inferred from DOI database lookup

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

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based on heuristic

inferred from DOI database lookup

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Molecular Analysis and Developmental Expression of the Focal Adhesion Kinase pp125FAK in Xenopus laevis

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Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

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based on heuristic

inferred from DOI database lookup

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

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based on heuristic

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Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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based on heuristic

inferred from DOI database lookup

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1 reference

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1 reference

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1 reference

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based on heuristic

inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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inferred from DOI database lookup

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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inferred from DOI database lookup

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inferred from DOI database lookup

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7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Leupaxin is a novel LIM domain protein that forms a complex with PYK2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein tyrosine phosphatase 1B negatively regulates integrin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytokine signaling through the novel tyrosine kinase RAFTK in Kaposi's sarcoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated activation of focal adhesion kinase is independent of focal adhesion formation or integrin activation. Studies with activated and inhibitory beta3 cytoplasmic domain mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic T lymphocytes express a beta3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrins, adhesion and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirements for localization of p130cas to focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Pp125FAK is required for stretch dependent morphological response of endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of two proline-rich sequences of cell adhesion kinase beta with SH3 domains of p130Cas-related proteins and a GTPase-activating protein, Graf

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Entamoeba histolytica: involvement of pp125FAK in collagen-induced signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

beta1-integrin cytoplasmic subdomains involved in dominant negative function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of integrin-stimulated sites of serine phosphorylation in FRNK, the separately expressed C-terminal domain of focal adhesion kinase: a potential role for protein kinase A.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the kinase activity essential for tyrosine phosphorylation of p130Cas in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of beta1A integrin functions by tyrosine residues in the beta1 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal adhesion kinase (p125FAK) and paxillin are substrates for sphingomyelinase-induced tyrosine phosphorylation in Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Adhesion-growth factor interactions during differentiation: an integrated biological response

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential signaling by the focal adhesion kinase and cell adhesion kinase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin signalling and tyrosine phosphorylation: just the FAKs?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrins: emerging paradigms of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of cell cycle progression by fibronectin matrix architecture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid recruitment of p120RasGAP and its associated protein, p190RhoGAP, to the cytoskeleton during integrin mediated cell-substrate interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell migration: regulation of force on extracellular-matrix-integrin complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated signaling events in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A suppressive role of p125FAK protein tyrosine kinase in hydrogen peroxide-induced apoptosis of T98G cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of mitogen-activated protein kinase activation by the cytoplasmic domain of the alpha6 integrin subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of focal adhesion kinase gene and invasive cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of focal adhesion kinase by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Human T and B Lymphocytes Express a Structurally Conserved Focal Adhesion Kinase, pp125FAK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Diphtheria toxin-mediated ablation of parietal cells in the stomach of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine kinase cell signaling pathways of rat mesangial cells in 3-dimensional cultures: response to fetal bovine serum and platelet-derived growth factor-BB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A beta peptide enhances focal adhesion kinase/Fyn association in a rat CNS nerve cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase C and F-actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G-proteins and amyloid beta protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the cell cycle by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

based on heuristic

inferred from DOI database lookup

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