(Q30469063)

21 June 2017

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title

Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins (English)

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21 June 2017

Parsons JT

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21 June 2017

publication date

1 April 1996

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Current Opinion in Cell Biology

21 June 2017

published in

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21 June 2017

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21 June 2017

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21 June 2017

page(s)

146-152

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Integrins: versatility, modulation, and signaling in cell adhesion

21 June 2017

cites work

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Signal transduction through integrins: a central role for focal adhesion kinase?

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Integrins: emerging paradigms of signal transduction

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Focal adhesion kinase and associated proteins

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Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

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pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

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Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

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Expression of an N-terminally truncated form of human focal adhesion kinase in brain

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Molecular Analysis and Developmental Expression of the Focal Adhesion Kinase pp125FAK in Xenopus laevis

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

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Integrins and signal transduction pathways: the road taken

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Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

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Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.

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Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

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Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

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Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

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Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

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pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

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7 January 2021

Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage

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Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

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7 January 2021

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

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Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

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7 January 2021

Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2

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Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin

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7 January 2021

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

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The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases

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7 January 2021

Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin

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7 January 2021

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

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7 January 2021

Profilin: at the crossroads of signal transduction and the actin cytoskeleton

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7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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7 January 2021

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

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7 January 2021

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Identifiers

DOI

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21 June 2017

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