(Q28141934)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0035004

phosphatidylinositol-3-phosphate binding

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0032266

phosphatidylinositol 3-kinase binding

1 reference

Gene Ontology release 2020-05-02

1 reference

S J Leevers

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B Vanhaesebroeck

series ordinal

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M D Waterfield

series ordinal

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language of work or name

English

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publication date

April 1999

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published in

Current Opinion in Cell Biology

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volume

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issue

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page(s)

219-25

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cites work

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Inositol lipid pathways turn turtle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Vesicular transport. Sticky fingers grab a lipid

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

FYVE fingers bind PtdIns(3)P

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

A functional PtdIns(3)P-binding motif

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Regulatory recruitment of signalling molecules to the cell membrane by pleckstrinhomology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Molecules in the ARF orbit

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Vesicle traffic: get your coat!

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphoinositide 3-OH kinase activates the beta2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Regulation of phosphoinositide-specific phospholipase C isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

A surprising function for the PTEN tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980029-5

7 January 2021

10.1016/S0955-0674(99)80029-5

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

10209156

1 reference

Consolidated OpenCitations Corpus – April 2017