(Q24677047)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

0 references

1 reference

Transformation related protein 53

1 reference

H2A.X variant histone

1 reference

Ataxia telangiectasia mutated

1 reference

MRE11A homolog A, double strand break repair nuclease

1 reference

Checkpoint kinase 1

1 reference

Serine/threonine-protein kinase ATR

1 reference

Bloom syndrome, RecQ like helicase

1 reference

Transformation related protein 53 binding protein 1

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Ana I Robles

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Steven P Linke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Natasha I Sinogeeva

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Ran Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Irene M Ward

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Arkady Celeste

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

André Nussenzweig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Junjie Chen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Thanos D Halazonetis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Curtis C Harris

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

1 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

166

1 reference

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1 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

801-813

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

1 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Diverged nuclear localization of Werner helicase in human and mouse cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Regulation and localization of the Bloom syndrome protein in response to DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

The Bloom's syndrome gene product promotes branch migration of holliday junctions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Megabase chromatin domains involved in DNA double-strand breaks in vivo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Two cellular proteins that bind to wild-type but not mutant p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Functional interaction of p53 and BLM DNA helicase in apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Genomic instability in mice lacking histone H2AX

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Chk1 and Chk2 kinases in checkpoint control and cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

RecQ helicases: caretakers of the genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Cell cycle checkpoint signaling through the ATM and ATR kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

p53's double life: transactivation-independent repression of homologous recombination.

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Identifying Inhibitors of ATM and ATR Kinase Activities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

53BP1, a mediator of the DNA damage checkpoint

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

The BLM helicase is necessary for normal DNA double-strand break repair.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

DNA helicases, genomic instability, and human genetic disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Nuclear organization of DNA replication in primary mammalian cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

Neocarzinostatin-induced DNA base release accompanied by staggered oxidative cleavage of the complementary strand

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172115

30 May 2018

Identifiers

DOI

10.1083/JCB.200405128

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

15364958

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364958%20AND%20SRC:MED&resulttype=core&format=json