(Q22253476)

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CrkII participation in the cellular effects of growth hormone and insulin-like growth factor-1. Phosphatidylinositol-3 kinase dependent and independent effects

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CrkII participation in the cellular effects of growth hormone and insulin-like growth factor-1. Phosphatidylinositol-3 kinase dependent and independent effects (English)

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CRK proto-oncogene, adaptor protein

1 reference

GOA release 2020-03-11

regulation of transcription by RNA polymerase II

1 reference

GOA release 2020-03-11

author name string

E L Goh

1

author given names

E L

author last names

Goh

1 reference

PubMed publication ID

28 March 2023

T Zhu

2

author given names

T

author last names

Zhu

1 reference

PubMed publication ID

28 March 2023

S Yakar

3

author given names

S

author last names

Yakar

1 reference

PubMed publication ID

28 March 2023

D LeRoith

4

author given names

D

author last names

LeRoith

1 reference

PubMed publication ID

28 March 2023

P E Lobie

5

author given names

P E

author last names

Lobie

1 reference

PubMed publication ID

28 March 2023

language of work or name

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publication date

9 June 2000

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Journal of Biological Chemistry

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275

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23

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17683-92

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Mode of action of pituitary growth hormone on target cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Growth hormone (GH) and insulin-like growth factor-I (IGF-I) treatment of the GH-deficient dwarf rat: differential effects on IGF-I transcription start site expression in hepatic and extrahepatic tissues and lack of effect on type I IGF receptor mRN

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Molecular mechanism of growth hormone action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

The functional role of CrkII in actin cytoskeleton organization and mitogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Prolactin induced tyrosine phosphorylation of p59fyn may mediate phosphatidylinositol 3-kinase activation in Nb2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Identification of amino acid residues required for a specific interaction between Src-tyrosine kinase and proline-rich region of phosphatidylinositol-3' kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

The Proto-oncogene Product c-Crk Associates with Insulin Receptor Substrate-1 and 4PS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Activation of a CrkL-stat5 signaling complex by type I interferons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating factor or erythropoietin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

Platelet-derived growth factor-induced formation of tensin and phosphoinositide 3-kinase complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

21 January 2018

c-Abl kinase regulates the protein binding activity of c-Crk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

7 January 2021

based on heuristic

inferred from DOI database lookup

The proto-oncogene product c-Crk associates with insulin receptor substrate-1 and 4PS. Modulation by insulin growth factor-I (IGF) and enhanced IGF-I signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001972200

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1074/JBC.M001972200

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