(Q55920868)

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Vicky A. Blakesley

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Zila Shen-Orr

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Marce Jimenez

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Bethel Stannard

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Ling-Mei Wang

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Jacalyn Pierce

Journal of Biological Chemistry

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language of work or name

English

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publication date

19 April 1996

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published in

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volume

271

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issue

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page(s)

9287-9290

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cites work

A novel viral oncogene with structural similarity to phospholipase C

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Two species of human CRK cDNA encode proteins with distinct biological activities

21 January 2018

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C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

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CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

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Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk

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The new elements of insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains

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IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

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Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor

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Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

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The function of GRB2 in linking the insulin receptor to Ras signaling pathways

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Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

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A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

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Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

21 January 2018

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Role of IRS-2 in insulin and cytokine signalling

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

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Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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Identification of a ten-amino acid proline-rich SH3 binding site

21 January 2018

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SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl

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Direct demonstration of an intramolecular SH2-phosphotyrosine interaction in the Crk protein

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Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

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