(Q36299512)

13 August 2017

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title

Break on through to the other side-biophysics and cell biology shed light on cell-penetrating peptides (English)

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13 August 2017

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Mariola Fotin-Mleczek

series ordinal

object named as

Mariola Fotin-Mleczek

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13 August 2017

Rainer Fischer

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13 August 2017

Hansjörg Hufnagel

series ordinal

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13 August 2017

Roland Brock

series ordinal

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13 August 2017

publication date

1 December 2005

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13 August 2017

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13 August 2017

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13 August 2017

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13 August 2017

page(s)

2126-2142

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Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

13 August 2017

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Cargo delivery kinetics of cell-penetrating peptides

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Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells

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Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells

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Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins

21 January 2018

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Tat-calpastatin fusion proteins transduce primary rat cortical neurons but do not inhibit cellular calpain activity

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Can transcription factors function as cell–cell signalling molecules?

21 January 2018

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Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization

21 January 2018

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Translocation of the pAntp peptide and its amphipathic analogue AP-2AL.

21 January 2018

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The antennapedia peptide penetratin translocates across lipid bilayers - the first direct observation.

21 January 2018

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Plasmon-waveguide resonance and impedance spectroscopy studies of the interaction between penetratin and supported lipid bilayer membranes

21 January 2018

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Orientation and Conformation of Cell-Penetrating Peptide Penetratin in Phospholipid Vesicle Membranes Determined by Polarized-Light Spectroscopy

21 January 2018

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Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential

21 January 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

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Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis

21 January 2018

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21 January 2018

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Facing inward from compartment shores: how many pathways were we looking for?

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How Viruses Enter Animal Cells

21 January 2018

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21 January 2018

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21 January 2018

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Penetration of protein toxins into cells

21 January 2018

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The many ways to cross the plasma membrane.

21 January 2018

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Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis

21 January 2018

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Getting hydrophilic compounds into cells: lessons from homeopeptides

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular import of functional peptides to block intracellular signaling

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Genetic engineering of proteins with cell membrane permeability

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions

21 January 2018

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Peptide-based intracellular shuttle able to facilitate gene transfer in mammalian cells

21 January 2018

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Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

21 January 2018

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Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The cationic cell-penetrating peptide CPP(TAT) derived from the HIV-1 protein TAT is rapidly transported into living fibroblasts: optical, biophysical, and metabolic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

New transport peptides broaden the horizon of applications for peptidic pharmaceuticals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

A D-amino acid peptide inhibitor of NF-kappa B nuclear localization is efficacious in models of inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Conjugation of poly-L-lysine to albumin and horseradish peroxidase: a novel method of enhancing the cellular uptake of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular uptake of the tat protein from human immunodeficiency virus

21 January 2018

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A peptide carrier for the delivery of biologically active proteins into mammalian cells.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Loligomers: design of de novo peptide-based intracellular vehicles

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Membrane binding and translocation of cell-penetrating peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Protein transduction domains of HIV-1 and SIV TAT interact with charged lipid vesicles. Binding mechanism and thermodynamic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate: binding mechanism and thermodynamic parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Oligocarbamate molecular transporters: design, synthesis, and biological evaluation of a new class of transporters for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Tat cell-penetrating peptide has the characteristics of a poly(proline) II helix in aqueous solution and in SDS micelles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Ligand binding to heparan sulfate proteoglycans induces their aggregation and distribution along actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The ability of chloroquine to prevent tat-induced cytokine secretion by monocytes is implicated in its in vivo anti-human immunodeficiency virus type 1 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Protein cargo delivery properties of cell-penetrating peptides. A comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Pathway for polyarginine entry into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Possible existence of common internalization mechanisms among arginine-rich peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Physico-chemical requirements for cellular uptake of pAntp peptide. Role of lipid-binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Anion-mediated transfer of polyarginine across liquid and bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Studies on the internalization mechanism of cationic cell-penetrating peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Charge-dependent translocation of the Trojan peptide penetratin across lipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Penetratin-induced aggregation and subsequent dissociation of negatively charged phospholipid vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The position of the cell penetrating peptide penetratin in SDS micelles determined by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Translocation of human calcitonin in respiratory nasal epithelium is associated with self-assembly in lipid membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular internalization of enhanced green fluorescent protein ligated to a human calcitonin-based carrier peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

In vitro gene delivery by a novel human calcitonin (hCT)-derived carrier peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Novel daunorubicin-carrier peptide conjugates derived from human calcitonin segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular internalization of human calcitonin derived peptides in MDCK monolayers: a comparative study with Tat(47-57) and penetratin(43-58).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Design, synthesis, and characterization of a model peptide having potent calcitonin-like biological activity: implications for calcitonin structure/activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Interactions of the human calcitonin fragment 9-32 with phospholipids: a monolayer study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Structural investigations of a human calcitonin-derived carrier peptide in a membrane environment by solid-state NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

NMR solution structure and position of transportan in neutral phospholipid bicelles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Insight into the mechanism of internalization of the cell-penetrating carrier peptide Pep-1 through conformational analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Primary Amphipathic Cell-Penetrating Peptides: Structural Requirements and Interactions with Model Membranes†

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Combination of a new generation of PNAs with a peptide-based carrier enables efficient targeting of cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Antimicrobial peptides of multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Mode of action of membrane active antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Bacterial cell penetration by beta3-oligohomoarginines: indications for passive transfer through the lipid bilayer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Bactericidal antisense effects of peptide-PNA conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Barrel-stave model or toroidal model? A case study on melittin pores.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Mechanism and kinetics of delta-lysin interaction with phospholipid vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Kinetics of dye efflux and lipid flip-flop induced by delta-lysin in phosphatidylcholine vesicles and the mechanism of graded release by amphipathic, alpha-helical peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Application of a novel analysis to measure the binding of the membrane-translocating peptide penetratin to negatively charged liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Role of LBPA and Alix in multivesicular liposome formation and endosome organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cationic TAT peptide transduction domain enters cells by macropinocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Tumor imaging by means of proteolytic activation of cell-penetrating peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Potential peptide carriers: amphipathic proline-rich peptides derived from the N-terminal domain of gamma-zein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Receptor/transporter-independent targeting of functional peptides across the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Nuclear trafficking of macromolecules by an oligopeptide derived from Vpr of human immunodeficiency virus type-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Translocation activity of C-terminal domain of pestivirus Erns and ribotoxin L3 loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

The Retro-inverso Form of a Homeobox-Derived Short Peptide Is Rapidly Internalized by Cultured Neurons: A New Basis for an Efficient Intracellular Delivery System

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Peptide dendrimers based on polyproline helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Synthesis of functional proteins by mixing peptide motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Translocation of a beta-peptide across cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cellular uptake studies with beta-peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

beta-Homolysine oligomers: a new class of Trojan carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cell penetrable peptoid carrier vehicles: synthesis and evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Messenger proteins: homeoproteins, TAT and others

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Uptake of cell-penetrating peptides is dependent on peptide-to-cell ratio rather than on peptide concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Cell membrane translocation of the N-terminal (1-28) part of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

Consequences of Nonlytic Membrane Perturbation to the Translocation of the Cell Penetrating Peptide Pep-1 in Lipidic Vesicles†

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500044

21 January 2018

Identifiers

DOI

10.1002/CBIC.200500044

1 reference

release_iiiziqrtszhqjkkpkplcl5rtzu

13 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/iiiziqrtszhqjkkpkplcl5rtzu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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