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Patients with celiac disease may have normal weight or may even be overweight

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Abstract

Background

It is believed that patients with celiac disease (CeD) are likely to be underweight. Data from west suggest that 8 % to 40 % of them can be overweight or obese. We reviewed data on body mass index (BMI) of our patients with CeD and derived the correlations between BMI and other disease characteristics.

Methods

We retrospectively studied case records of 210 adolescent and adult patients with CeD at the Celiac Disease Clinic. We classified BMI as underweight, normal weight, overweight, and obese based on the Consensus Statement for Diagnosis of Obesity, Abdominal Obesity and the Metabolic Syndrome for Asian Indians for those with age >18 years and revised Indian Association of Pediatrics BMI-for-age charts for those between 12 and 18 years.

Results

Of 210 patients, 76 (36.2 %) were underweight, 115 (54.8 %) were normal weight, 13 (6.2 %) were overweight, and 6 (2.9 %) were obese. There was no difference in the proportion of underweight between male and female patients with CeD. The mean age of underweight patients was similar to those having normal or overweight. There was no difference in the mean duration of symptoms; frequencies of diarrhea, anorexia, and weakness; anemia; titer of anti-tissue transglutaminase antibody; and severity of villous atrophy in those with underweight or normal weight or overweight.

Conclusions

In our practice, only one third of patients with CeD had low BMI. A diagnosis of CeD should not be excluded if patient has normal or high BMI.

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Authors and Affiliations

  1. Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India

    Isha Singh, Abhishek Agnihotri, Aishwairya Sharma, Anil K. Verma, Vineet Ahuja & Govind K. Makharia

  2. Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India

    Prasenjit Das & Siddhartha Datta Gupta

  3. Department of Biostatistics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India

    Bhaskar Thakur & V. Sreenivas

Authors
  1. Isha Singh
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  2. Abhishek Agnihotri
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  3. Aishwairya Sharma
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  4. Anil K. Verma
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  5. Prasenjit Das
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  6. Bhaskar Thakur
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  7. V. Sreenivas
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  8. Siddhartha Datta Gupta
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  9. Vineet Ahuja
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  10. Govind K. Makharia
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Corresponding author

Correspondence to Govind K. Makharia.

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Conflict of interest

IS, AA, AS, AKV, PD, BT, VS, SDG, VA, and GKM declare that they have no competing interests.

Informed consent

The authors declare that the study was performed in a manner to conform with the Helsinki Declaration of 1975, as revised in 2000 and 2008 concerning Human and Animal Rights. As the study was a retrospective analysis of the database without identifying data about any individual, we did not obtain informed consent from individual participants.

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Singh, I., Agnihotri, A., Sharma, A. et al. Patients with celiac disease may have normal weight or may even be overweight. Indian J Gastroenterol 35, 20–24 (2016). https://doi.org/10.1007/s12664-016-0620-9

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  • DOI: https://doi.org/10.1007/s12664-016-0620-9

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