Skip to main content
Osteoporosis is a disease characterised by low bone mass and microarchitectural deterioration of bone tissue, leading to increased bone fragility and a consequent increase in fracture risk, especially among postmenopausal women.... more
Osteoporosis is a disease characterised by low bone mass and microarchitectural deterioration of bone tissue, leading to increased bone fragility and a consequent increase in fracture risk, especially among postmenopausal women. Management strategies for osteoporosis focus on reducing modifiable risk factors such as poor nutrition, insufficient physical activity, smoking, and heavy alcohol consumption. The aim of this systematic review is to examine the effects of lifestyle interventions on bone health in women at high risk of osteoporosis INCLUSION CRITERIA: We included randomised controlled trials that examined the effectiveness of lifestyle interventions. The participants consisted of adult women who have had osteoporosis, osteopenia, or were at high-risk of developing osteoporosis. Lifestyle interventions included exercise, diet, and education. The outcomes of bone health were bone mineral density, event (fall, fracture), balance, and quality of life. We conducted a comprehensive search of the published literature using a three-phase approach in English and Korean languages up until September 2009. Two independent reviewers appraised all reports using standardised critical appraisal tools from the Joanna Briggs Institute that were specific to experimental research designs. Quantitative data was extracted from papers using the standardised data extraction tool from Joanna Briggs Institute. Quantitative papers were pooled wherever possible to a statistical meta-analysis using the Joanna Briggs Institute Meta Analysis of Statistics Assessment and Review Instrument. The search identified 700 unique studies; we appraised 28 studies and included a total of 25 randomised controlled trials in the final study; three studies were excluded because of poor methodological quality. Strength exercises had a positive effect on fracture. Aerobic exercises had a positive impact on lumbar bone mineral density, fall, and balance. Soy protein supplementation was effective for improving lumbar bone mineral density while vitamin K supplementation had a positive effect on of femur bone mineral density. Calcium supplementation had a positive impact on femur and lumbar bone mineral density. The combination of exercise, calcium, and vitamin D supplementation was effective for improving lumbar bone mineral density, risk of fall, and balance. Self-management programs for better bone health had a positive effect on balance and quality of life. The results indicate that lifestyle interventions including exercise and taking daily calcium and vitamin D supplementation are beneficial for improving bone health in women at high risk of osteoporosis. However, additional carefully designed randomised controlled trials studies with larger patient populations are needed to more precisely identify the effects of intervention. It is recommended to engage in a combination of regular exercise and daily calcium and vitamin D supplementation with consideration of age, menopausal status, and bone mineral density for women with a high risk of developing osteoporosis. Effects of combined intervention of lifestyle components should be evaluated in large, carefully designed randomised controlled trials.
Climate change is closely linked to rising levels of atmospheric carbon dioxide and methane due to human activities, and soaring temperatures might themselves pose a risk to natural carbon sequestration in the land. This editorial... more
Climate change is closely linked to rising levels of atmospheric carbon dioxide and methane due to human activities, and soaring temperatures might themselves pose a risk to natural carbon sequestration in the land. This editorial introduces three papers in the current issue exploring the adverse effects on mental health of climate-related loss of biodiversity and cultural heritage markers and the beneficial effects of adopting a plant-based diet. It also suggest three simple steps that clinicians can themselves take to act against climate change: choosing and recommending a plant-based diet, reducing personal use of fossil fuels and integrating climate change in discourse in all areas of their professional work.
In this issue, three papers discuss the issue of the brain drain: of psychiatrists from Egypt and Nigeria, and of nurses from East Africa. They explore the complexities of professional migration and its impact on the health of populations... more
In this issue, three papers discuss the issue of the brain drain: of psychiatrists from Egypt and Nigeria, and of nurses from East Africa. They explore the complexities of professional migration and its impact on the health of populations in source and recipient countries; they also review how recommendations for changes in policy and practice might influence the so-called ‘push’ and ‘pull’ factors that aggravate the brain drain.
The Lancet Commission summarises some of the history of mental health concepts, recent developments in scientific understanding, mental health programmes and threats to progress, and proposes a way forward. Although ostensibly aiming to... more
The Lancet Commission summarises some of the history of mental health concepts, recent developments in scientific understanding, mental health programmes and threats to progress, and proposes a way forward. Although ostensibly aiming to reframe global mental health within the paradigm of sustainable development, in practice it has taken a narrower academic perspective rather than a generic approach to health and social sector reform, leading to much less of an integrated implementation focus than would have been useful.
Part I. The Context of Health and Mental Health Programmes: 1. Updating 1789 2. Doubts about three of the many dogmas of development 3. Overlaps and confusions 4. Nearly forgotten: mental health needs of an urbanized planet 5. The Mozart... more
Part I. The Context of Health and Mental Health Programmes: 1. Updating 1789 2. Doubts about three of the many dogmas of development 3. Overlaps and confusions 4. Nearly forgotten: mental health needs of an urbanized planet 5. The Mozart effect and Keshan disease 6. The paradoxes about psychiatry 7. On advice and consultation Part II. Mental Health and Medicine: 8. Psychiatry in the framework of primary health care: a threat or boost for psychiatry? 9. The limits of mental health care in general medical services 10. The mental health adventure of the World Health Organization 11. Mental health care for the elderly? Another thirty years to wait 12. On words I like to hate Part III. Psychiatry and Mental Health Programmes: 13. Assessing needs for psychiatric services 14. Why are mental and neurological disorders not being prevented? 15. The seven vices of psychiatry 16. Brueghel's Everyman: a cover page for a book on research in psychiatry 17. And then there were five ... 18. Enabling 19. Psychiatry in developing countries Index.
There is limited information about stakeholder perceptions of health service provision in low- and middle-income countries. We conducted a cross-sectional survey of 821 stakeholders of the community mental health services in Pemba Island,... more
There is limited information about stakeholder perceptions of health service provision in low- and middle-income countries. We conducted a cross-sectional survey of 821 stakeholders of the community mental health services in Pemba Island, Zanzibar, Tanzania. The aim was to obtain systematic information about coverage, barriers, accountability and room for improvement as a baseline before implementation of a new mental health policy to strengthen mental health services.
Integration of mental health into primary care is essential to meet population needs yet faces many challenges if such projects are to achieve impact and be sustainable in low income countries alongside other competing priorities. This... more
Integration of mental health into primary care is essential to meet population needs yet faces many challenges if such projects are to achieve impact and be sustainable in low income countries alongside other competing priorities. This paper describes the rationale and progress of a collaborative project in Kenya to train primary care and community health workers about mental health and integrate mental health into their routine work, Within a health systems strengthening approach. So far 1877 health workers have been trained. The paper describes the multiple challenges faced by the project, and reviews the mechanisms deployed which have strengthened its impact and sustainability to date.
This paper describes the Household Survey from the National Survey of Psychiatric Morbidity. This covered a sample drawn at random from the population of Britain, with the exception of the Highlands and Islands of Scotland. The Postcode... more
This paper describes the Household Survey from the National Survey of Psychiatric Morbidity. This covered a sample drawn at random from the population of Britain, with the exception of the Highlands and Islands of Scotland. The Postcode Address file was used as the sampling frame. Nearly 13000 adults aged 16-65 were selected for interview, of whom 10108 (79.4%) were successfully interviewed. Eight per cent could not be contacted and 13% refused interview. Psychiatric assessment was carried out by lay interviewers using the CIS-R. Subjects were also screened for psychosis, and screen-positive individuals were examined by psychiatrists using SCAN. Sixteen per cent of subjects scored above the standard cut-off of 12 on the CIS-R. The overall 1-week prevalence of neurotic disorder was 12.3% in males and 19.5% in females. Unmarried and post-marital groups had high rates of disorder, as did single parents and people living on their own. Respondents in Social Class I had notably lower rates of neurotic disorder than the remainder of the sample. Unemployment was strongly associated with disorder. Subjects living in urban areas had a higher overall prevalence, but there was no significant variation by region. Black respondents had higher rates of disorders that were entirely explained by their age, family type and social class. Individual neurotic disorders were all significantly commoner in women, with the exception of panic disorder. The 1-year prevalence of functional psychoses was 4 per 1000, with no sex difference. Alcohol and drug dependence was considerably more prevalent in men. For the first time, the survey provides data on the prevalence and correlates of psychiatric disorder on a nationwide sample that can be used to inform equitable and effective national psychiatric services.
Background Suicide is an important contributor to the burden of mental health disorders, but community-based suicide data are scarce in many low- and middle-income countries (LMIC) including Kenya. Available data on suicide underestimates... more
Background Suicide is an important contributor to the burden of mental health disorders, but community-based suicide data are scarce in many low- and middle-income countries (LMIC) including Kenya. Available data on suicide underestimates the true burden due to underreporting related to stigma and legal restrictions, and under-representation of those not utilizing health facilities. Methods We estimated the cumulative incidence of suicide via verbal autopsies from the Health and Demographic Surveillance System (HDSS) in Kisumu County, Kenya. We then used content analysis of open history forms among deaths coded as accidents to identify those who likely died by suicide but were not coded as suicide deaths. We finally conducted a case-control study of suicides (both verbal autopsy confirmed and likely suicides) compared to accident-caused deaths to assess factors associated with suicide in this HDSS. Results A total of 33 out of 4306 verbal autopsies confirmed suicide as the cause of ...
Traditional and complementary systems of medicine include a broad range of practices, which are commonly embedded in cultural milieus and refl ect community beliefs, experiences, religion, and spirituality. Two major components of this... more
Traditional and complementary systems of medicine include a broad range of practices, which are commonly embedded in cultural milieus and refl ect community beliefs, experiences, religion, and spirituality. Two major components of this system are discernible: complementary alternative medicine and traditional medicine, with diff erent clientele and correlates of patronage. Evidence from around the world suggests that a traditional or complementary system of medicine is commonly used by a large number of people with mental illness. Practitioners of traditional medicine in low-income and middle-income countries fi ll a major gap in mental health service delivery. Although some overlap exists in the diagnostic approaches of traditional and complementary systems of medicine and conventional biomedicine, some major diff erences exist, largely in the understanding of the nature and cause of mental disorders. Treatments used by providers of traditional and complementary systems of medicine...
Abstract: Evidence suggests substance abuse in Tanzania is a growing public health problem. A random sample of 899 adults aged 15-59 in two urban sites of differing levels of poverty surveyed alcohol, tobacco and illicit substance use.... more
Abstract: Evidence suggests substance abuse in Tanzania is a growing public health problem. A random sample of 899 adults aged 15-59 in two urban sites of differing levels of poverty surveyed alcohol, tobacco and illicit substance use. Rates of substance use were 17.2%. 8.7 % and 0.8 % for alcohol, tobacco and cannabis, respectively. Living in the less affluent area was associated with higher lifetime rates of tobacco and alcohol use. Substance use is less prevalent in Tanzania than in richer countries, but lifetime consumption is higher in poorer areas. The association of substance use with a range of socio-economic factors warrants further research.
Abstract: There have been few epidemiological surveys to establish prevalence and associated risk factors of psychosis in Sub-Saharan Africa. This paper reports a population-based epidemiological survey in rural Kenya of the prevalence of... more
Abstract: There have been few epidemiological surveys to establish prevalence and associated risk factors of psychosis in Sub-Saharan Africa. This paper reports a population-based epidemiological survey in rural Kenya of the prevalence of psychotic symptoms and their relationship with demographic, socio-economic and other risk factors. A random sample of 2 % of all adults living in Maseno, Kisumu District of Nyanza province, Kenya

And 413 more

Factors influencing cross-national diffusion of mental health policy are important to understand but complex to research. This commentary discusses Shen’s research study on cross-national diffusion of mental health policy; examines the... more
Factors influencing cross-national diffusion of mental health policy are important to understand but complex to research. This commentary discusses Shen’s research study on cross-national diffusion of mental health policy; examines the extent to which the three questions researched by Shen (whether countries are more likely to have a mental health policy (a) the earlier a country becomes a member of World Health Organization (WHO), (b) the more international aid a country receives, and (c) the more neighbouring countries already have a mental health policy) are in fact able to assess WHO’s impact on cross-national diffusion of mental health policy. The commentary then suggests a range of more specific questions which may be used to further elucidate the impact of WHO on an individual country, and considers the relative value of published mental health policy compared with the integration of mental health into national health sector strategies and other sector reforms, and concludes with a call for more integration of mental health across all WHO activities at international, regional and country levels.