Sujata Basu
Jaypee Institute of Information Technology, Biotechnology, Department Member
- Social Entrepreneurship & Innovation, Biotechnology, OXIDATIVE STRESS AND FREE RADICAL BIOLOGY, Medicinal plants for cancer diabetes hypertensive and nutraceutical developments, Mitochondria, Molecular and cellular biology, and 6 moreNeuroscience, Clinical Biochemistry, Biochemistry and cell biology, Membrane Proteins, Protein Engineering, and Mammalian Cell Cultureedit
- Dynamic and professional biochemist and biotechnologist bringing forth valuable research industry experience in driving innovation in healthcare and life sciences. A proven track record of working collaboratively with researchers, healthcare professionals, and management leaders in strategic problem-solving and customer relationships, and effective communication of complex medical concepts to diverse audiences. Research areas include oxidative stress in diabetic complicat... moreDynamic and professional biochemist and biotechnologist bringing forth valuable research industry experience in driving innovation in healthcare and life sciences. A proven track record of working collaboratively with researchers, healthcare professionals, and management leaders in strategic problem-solving and customer relationships, and effective communication of complex medical concepts to diverse audiences.
Research areas include oxidative stress in diabetic complications, mitochondrial biochemical interplay, neuroscience, and respiratory research.
Publication areas – Oxidative stress and diabetes; Antioxidants and disease; Antidiabetic medicinal plants and phytoconstituents; Medical Biochemistry; Human Physiology and Anatomy; Basics of Zoology; Neurodegenerative disorders and pathway interplays; Parkinson’s disorder, Cellular interactions of protein.
Interested in scientific research tasks, publishing manuscripts, journal management, supervising laboratory activities, project management, and teaching and mentorship for researchers in academic/healthcare domains.edit
The glial cells along with cells of hematopoietic origin and microvascular endothelia work together to maintain the normal development and/or functioning of the nervous system. Disruption in functional coordination among these cells... more
The glial cells along with cells of hematopoietic origin and microvascular endothelia work together to maintain the normal development and/or functioning of the nervous system. Disruption in functional coordination among these cells interrupts the efficiency of the nervous system, leading to neurodegeneration. Various proteins in the nerve cells maintain the normal signaling mechanism with these cells and throughout the body. Structural/functional disorganization of these proteins causes neurodegenerative disorders. The molecular mechanisms involved in these phenomena are yet to be explored extensively from therapeutic perspectives. Through this chapter, the authors have elaborated on less known protein Bcl-2 associated athanogene 3 (BAG3) involved in neurodegeneration. They have explored BAG3 protein and its role in neurodegeneration, protein homeostasis, its mechanism of action, its uses as a drug target, and its uses as a possible diagnostic marker of neurodegeneration.
Research Interests:
Vasicine molecule was first isolated in 1924 and most of the work on this molecule was done between 1960s-1980s. The plant Adhatoda vasica (Acanthaceae) is the main source of this molecule. This plant has been used in India for 2000 years... more
Vasicine molecule was first isolated in 1924 and most of the work on this molecule was done between 1960s-1980s. The plant Adhatoda vasica (Acanthaceae) is the main source of this molecule. This plant has been used in India for 2000 years for the treatment of respiratory ailments and for its abortifacient activities. It is surprising to note that, even if, it has been used effectively and extensively in the above mentioned areas since ancient times till date, and a huge amount of work has already been done on its derivative "Bromhexine", very few recent reports are available for its molecular mechanism of action. The present article is an attempt to compile the literature available for this molecule and to further analyze its probable potential use in the above areas, including few more other areas as well.