The important issue that causes medical error is poor communication between professions in provid... more The important issue that causes medical error is poor communication between professions in providing health services, ineffective teamwork collaboration, and unintegrated health services. The World Health Organization (WHO) triger the Interprofessional Education learning model as an integrated education system in health science students.The purpose of this study is to assess the teamwork formed after the IPE learning was applied to health science students at the professional level at the Universitas Sumatera Utara. Method. This research is a pre and post test design that was carried out by IPE learning in the area of Puskesmas Tuntungan Medan. The sample size is 20 students consisting of students from the faculty of medicine, nursing, pharmacy and public health at Universitas Sumatera Utara. The assessment of teamwork using the Team Work Score (TWS) questionnaire. Data analysis uses dependent t test.The results of this study indicate that the level of teamwork increases after IPE le...
Background: Relationship age, hemoglobin, and physical frailty have all been investigated in olde... more Background: Relationship age, hemoglobin, and physical frailty have all been investigated in older people with more than one chronic disease. There has been little analysis of the relationship between hemoglobin, age, physical frailty, Sirtuin1 (SIRT1) protein expression, and the gene polymorphism (SNP) rs7895833 A>G. The goal of this study was to find out how SIRT1 level, SNP rs7895833, hemoglobin, age, and physical frailty (frail score) are related in older Indonesian adults with comorbid chronic diseases. Methods: This was an observational study. Demographic and clinical data were retrieved from the electronic health records of Universitas Sumatera Utara Hospital, Medan, Indonesia. Physical frailty, SIRT1 level, and SNP rs7895833 were measured using an appropriate and valid method. Purposive sampling was used to determine the eligibility of 132 elderly adults from November 2022 to February 2023. Results: The indirect effect of hemoglobin on the frail score (FS) through age was...
A cross-sectional study was carried out at the H. Adam Malik hospital in Medan. Purposive samplin... more A cross-sectional study was carried out at the H. Adam Malik hospital in Medan. Purposive sampling was used to identify 55 research patients receiving hemodialysis (HD). Structured questionnaire interviews with patients were used to collect epidemiology data. Medical records and retested laboratory results were used to collect data on hemoglobin, qualitative C Reactive Protein (CRP), Blood urea nitrogen (BUN), and creatinine. The majority (72.7 %) of participants were male, with the 60–69 year age group accounting for 30.90%; Karo is the most ethnic group (41.8%), and hypertension is the most prevalent ailment (43.60%). The mean duration of HD was 36.00 months, with a hemoglobin (Hb) level of 9.37 g/dl. It can be shown that there is a negative and weak correlation between Hb and HD duration (r = -0.27) that is significant (p = 0.49) and has a coefficient of determination of 7%.
Open Access Macedonian Journal of Medical Sciences, 2022
BACKGROUND: Wet cupping is a non-pharmacological therapy that has been shown to assist hypertensi... more BACKGROUND: Wet cupping is a non-pharmacological therapy that has been shown to assist hypertensive patients with blood pressure reduction. However, the underlying mechanisms by which wet-cupping lowers blood pressure are currently unknown. More scientific investigation is necessary to explain the mechanism by which wet cupping lowers blood pressure, particularly the role of nitric oxide (NO). AIM: The study aimed to show the effect of wet cupping on NO levels in hypertensive patients. METHODS: A pre-experimental study using a single group pre-test and post-test design to monitor changes in blood NO levels and blood pressure in 45 hypertensive patients in Medan after 4 weeks of wet cupping therapy. The patients’ blood NO levels, as well as their systolic and diastolic blood pressures (SBP and DBP), were measured before and after 4 weeks of wet cupping. RESULTS: After 4 weeks of wet cupping, blood NO levels significantly increased (0.00704 mol/mL, p=0.039), while SBP and DBP levels s...
Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most ... more Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most recent best evidence, is gaining popularity. Individual clinical expertise is combined with the best available external clinical evidence derived from systematic research in the practice of EBM. The key and core of EBM is the hierarchical system for categorizing evidence. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system divides evidence quality into four categories: high, moderate, low, and very low. GRADE is based on the lowest quality of evidence for any of the outcomes that are critical to making a decision, reducing the risk of mislabeling the overall evidence quality, when evidence for a critical outcome is lacking. This principle is also used in acupuncture as a complementary and integrative treatment modality, but incorporating scientific evidence is more difficult due to a number of factors. The goal of this chapter is to discuss how to estab...
IOP Conference Series: Earth and Environmental Science, 2018
Primary dysmenorrhea is a gynecological disorder which most commonly occurs like a pain in the in... more Primary dysmenorrhea is a gynecological disorder which most commonly occurs like a pain in the initial menstruation. One ofthe attempts to handle dysmenorrhea is by using anon-pharmacological method such as herbal therapy which uses red ginger. The research was at Akbid and Akper Harapan Mama, Deli Serdang Regency, with pre-experimental design and one group pretest-posttest. The samples were 32 female students as the respondents, taken by using non-probability or consecutive sampling technique. PGF2a content measurement by ELISA, theintensity of pain by Visual Analogue Scale and analyzed by using Wilcoxon test. PGF2α content before giving red ginger capsule supplement median was 156.50 pg/ml (min-max: 57-1037 pg/ml), after giving it was 101 (min-max: 22-785), pain intensity before giving it in the mean score of 2 was 15 respondents (47%), after giving it in the mean score of 0 was 14 respondents (44%). The result of statistic test on PGF2α content before and after giving it was p-value = 0.001, and pain intensity before and after giving it was p < 0.001 which indicated that there was asignificant decrease in PGF2α and pain intensity after giving it. Red ginger capsule supplement could decrease PGF2α content during primary dysmenorrhea.
BACKGROUND: Interleukin (IL)-31 serum levels were significantly higher in hemodialysis patients w... more BACKGROUND: Interleukin (IL)-31 serum levels were significantly higher in hemodialysis patients with pruritus, whereas acupuncture in LI11 was shown to improve symptoms of pruritus. However, there is limited information that IL-31 serum levels that correlate with decreased dimensions of the pruritus after acupuncture in LI11 in a hemodialysis patient. AIM: The aim of the study was to demonstrate the impact of acupuncture in LI11 and IL-31 serum level and its correlation with dimensions of the pruritus in hemodialysis patients. METHODS: A randomized clinical trial has been carried out from August 2019 to December 2019 at H. Adam Malik General Hospital, Medan, Indonesia. Sixty patients underwent hemodialysis who were randomly allocated to two groups, one group got acupuncture in Quchi LI11 (intervention group), and the other group got a placebo (control group). IL-31 serum levels and pruritus were measured before and after 6 weeks of acupuncture in both groups. RESULTS: Acupuncture di...
Open Access Macedonian Journal of Medical Sciences, 2020
BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Maligna... more BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Malignancy is one of the most common causes of death in the world. T2DM is one of the risk factors for malignancy. This is caused by an increase in blood glucose levels (hyperglycemia) which will cause tissue hypoxia which can lead to malignancy. The cell adaptation response to hypoxia is relaxed by a marker called hypoxia-inducible factor-1 alpha (HIF-1α), where a condition converts hyperglycemia to a loss of cellular response to hypoxia in most complications of diabetes. AIM: The aim of this study was to determine level HIF-1α at T2DM with malignancy, where this study used the samples of the T2DM patients with malignancy and T2DM without malignancy. METHODS: The cross-sectional study design used the 89 samples of DM patients with and without malignancy who attended Murni Teguh Hospital in Medan of Indonesia country. The inclusion criteria of the samples were all the patients diagnosed with T2...
Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most ... more Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most recent best evidence, is gaining popularity. Individual clinical expertise is combined with the best available external clinical evidence derived from systematic research in the practice of EBM. The key and core of EBM is the hierarchical system for categorizing evidence. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system divides evidence quality into four categories: high, moderate, low, and very low. GRADE is based on the lowest quality of evidence for any of the outcomes that are critical to making a decision, reducing the risk of mislabeling the overall evidence quality, when evidence for a critical outcome is lacking. This principle is also used in acupuncture as a complementary and integrative treatment modality, but incorporating scientific evidence is more difficult due to a number of factors. The goal of this chapter is to discuss how to estab...
Background : The increasing prevalence of obesity is a major health problem worldwide. About 2.8 ... more Background : The increasing prevalence of obesity is a major health problem worldwide. About 2.8 million adults die each year linked to overweight and obesity. Individuals with overweight and obesity will experience an increased risk for health conditions. Several recent epidemiological studies have shown that obesity is associated with Chronic Kidney Disease (PGK). Method : This study aims to determine the description of Creatinine in Adult Obesity In Pasar 2 Tanjung Sari Medan 2017. This research is a descriptive study with cross sectional approach. Data collected from measurements of weight, height and plasma creatinine. Population in this study is all obese subject in the market 2 tanjung sari where the number of amps of 36 people. Results : High creatinine from normal age by age 30-39, 40-49 years and> 50 years each of 1 person. High creatinine from normal by sex is more common in men as many as 2 people, followed by women as much as 1 person. Creatinine is higher than norma...
BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Maligna... more BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Malignancy is one of the most common causes of death in the world. T2DM is one of the risk factors for malignancy. This is caused by an increase in blood glucose levels (hyperglycemia) which will cause tissue hypoxia which can lead to malignancy. The cell adaptation response to hypoxia is relaxed by a marker called hypoxia-inducible factor-1 alpha (HIF-1α), where a condition converts hyperglycemia to a loss of cellular response to hypoxia in most complications of diabetes. AIM: The aim of this study was to determine level HIF-1α at T2DM with malignancy, where this study used the samples of the T2DM patients with malignancy and T2DM without malignancy. METHODS: The cross-sectional study design used the 89 samples of DM patients with and without malignancy who attended Murni Teguh Hospital in Medan of Indonesia country. The inclusion criteria of the samples were all the patients diagnosed with T2...
Asma merupakan gangguan inflamasi kronik pada sistem pernafasan. Terjadi inflamasi yang khas kare... more Asma merupakan gangguan inflamasi kronik pada sistem pernafasan. Terjadi inflamasi yang khas karena disertai infiltrasi eosinofil, hal ini membedakan asma dari gangguan inflamasi jalan napas lainnya. Eosinofil merupakan mediator inflamasi utama pada asma. Eosinofil merangsang produksi mediator inflamasi, sitokin dan mediator. Pemahaman efek eosinofil menjadi dasar terapi asma, yaitu dengan menghambat sitokin, eosinofil dan menghambat interaksi antara eosinofil dan sel endotel. Selain itu menjadi dasar pengembangan modalitas terapi asma seperti Cyklophilin, Antibodi monoklonal antihuman IL-5, Anti Interleukin-1, Interleukin 10, Interleukin 12 dan Antihistamin. Pengetahuan ini memberi pemahaman mekanisme obat yang lazim digunakan seperti Glucocorticoid dan Anti leukotrine
Latar belakang: Buah Kurma selama ini masih menjadi suatu pertanyaan apakah dapat dikonsumsi oleh... more Latar belakang: Buah Kurma selama ini masih menjadi suatu pertanyaan apakah dapat dikonsumsi oleh penderita diabetes melitus tipe-2 yang terkontrol (diabetesi), tanpa mengacaukan kontrol glukosa darah (KGD). Tujuan: Untuk mengetahui perubahan KGD diabetesi setelah mengkonsumsi kurma. Bahan Dan Cara: Diteliti secara Uji klinis menyilang terhadap 36 orang diabetisi pria 22 orang dan wanita 14 orang dengan umur rata-rata 60±5,5 tahun, memakai Obat Hipoglikemik Oral (OHO) 28 orang dan Insulin 8 orang. Penelitian dilakukan 2 kali perlakuan, perlakuan-I, 18 orang mendapat 3 buah kurma dan 18 orang mendapat 1 buah pisang, KGD diukur sebelum memakan dan sesudah memakan masing-masing buah. Perlakuan-II seminggu kemudian kelompok yang sebelumnya mendapat 3 biji kurma diberikan 1 buah pisang dan begitu sebaliknya dan diukur KGD sebelum dan 2 jam sesudah memakan masing-masing buah. Hasil: Pada perlakuan-I Tidak ada perbedaan KGD sebelum menkonsumsi kurma dan 2 jam sesudah mengkonsumsi kurma (12...
The capacity of physical ability can be improved through doing an exercise which is according to ... more The capacity of physical ability can be improved through doing an exercise which is according to the intensity, duration and frequency. Exercise can improve the immunity system and influence the leucocyte. The number of pheripheral leucocyte can be the resource of information for the diagnostics and prognose the description of organ damage and the recovery after physical training. The purpose of this study to investigate the influence of moderate physical activity (MPA) to leucocyte count and diffrential leucocyte. This study is experimental with pretest-posttest group design. The subjects for this study is a women who are between 18-20 years old, they were 15 person. The subjects of study were given moderate intensity of physical activity in the form of stepping up and down test until the reached the targeted heartbeats which is 80% of the maximum heartbeats. The physical activity was done for a moment. Before doing the activity, the pheripheral blood was taken once, then the blood...
The important issue that causes medical error is poor communication between professions in provid... more The important issue that causes medical error is poor communication between professions in providing health services, ineffective teamwork collaboration, and unintegrated health services. The World Health Organization (WHO) triger the Interprofessional Education learning model as an integrated education system in health science students.The purpose of this study is to assess the teamwork formed after the IPE learning was applied to health science students at the professional level at the Universitas Sumatera Utara. Method. This research is a pre and post test design that was carried out by IPE learning in the area of Puskesmas Tuntungan Medan. The sample size is 20 students consisting of students from the faculty of medicine, nursing, pharmacy and public health at Universitas Sumatera Utara. The assessment of teamwork using the Team Work Score (TWS) questionnaire. Data analysis uses dependent t test.The results of this study indicate that the level of teamwork increases after IPE le...
Background: Relationship age, hemoglobin, and physical frailty have all been investigated in olde... more Background: Relationship age, hemoglobin, and physical frailty have all been investigated in older people with more than one chronic disease. There has been little analysis of the relationship between hemoglobin, age, physical frailty, Sirtuin1 (SIRT1) protein expression, and the gene polymorphism (SNP) rs7895833 A>G. The goal of this study was to find out how SIRT1 level, SNP rs7895833, hemoglobin, age, and physical frailty (frail score) are related in older Indonesian adults with comorbid chronic diseases. Methods: This was an observational study. Demographic and clinical data were retrieved from the electronic health records of Universitas Sumatera Utara Hospital, Medan, Indonesia. Physical frailty, SIRT1 level, and SNP rs7895833 were measured using an appropriate and valid method. Purposive sampling was used to determine the eligibility of 132 elderly adults from November 2022 to February 2023. Results: The indirect effect of hemoglobin on the frail score (FS) through age was...
A cross-sectional study was carried out at the H. Adam Malik hospital in Medan. Purposive samplin... more A cross-sectional study was carried out at the H. Adam Malik hospital in Medan. Purposive sampling was used to identify 55 research patients receiving hemodialysis (HD). Structured questionnaire interviews with patients were used to collect epidemiology data. Medical records and retested laboratory results were used to collect data on hemoglobin, qualitative C Reactive Protein (CRP), Blood urea nitrogen (BUN), and creatinine. The majority (72.7 %) of participants were male, with the 60–69 year age group accounting for 30.90%; Karo is the most ethnic group (41.8%), and hypertension is the most prevalent ailment (43.60%). The mean duration of HD was 36.00 months, with a hemoglobin (Hb) level of 9.37 g/dl. It can be shown that there is a negative and weak correlation between Hb and HD duration (r = -0.27) that is significant (p = 0.49) and has a coefficient of determination of 7%.
Open Access Macedonian Journal of Medical Sciences, 2022
BACKGROUND: Wet cupping is a non-pharmacological therapy that has been shown to assist hypertensi... more BACKGROUND: Wet cupping is a non-pharmacological therapy that has been shown to assist hypertensive patients with blood pressure reduction. However, the underlying mechanisms by which wet-cupping lowers blood pressure are currently unknown. More scientific investigation is necessary to explain the mechanism by which wet cupping lowers blood pressure, particularly the role of nitric oxide (NO). AIM: The study aimed to show the effect of wet cupping on NO levels in hypertensive patients. METHODS: A pre-experimental study using a single group pre-test and post-test design to monitor changes in blood NO levels and blood pressure in 45 hypertensive patients in Medan after 4 weeks of wet cupping therapy. The patients’ blood NO levels, as well as their systolic and diastolic blood pressures (SBP and DBP), were measured before and after 4 weeks of wet cupping. RESULTS: After 4 weeks of wet cupping, blood NO levels significantly increased (0.00704 mol/mL, p=0.039), while SBP and DBP levels s...
Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most ... more Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most recent best evidence, is gaining popularity. Individual clinical expertise is combined with the best available external clinical evidence derived from systematic research in the practice of EBM. The key and core of EBM is the hierarchical system for categorizing evidence. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system divides evidence quality into four categories: high, moderate, low, and very low. GRADE is based on the lowest quality of evidence for any of the outcomes that are critical to making a decision, reducing the risk of mislabeling the overall evidence quality, when evidence for a critical outcome is lacking. This principle is also used in acupuncture as a complementary and integrative treatment modality, but incorporating scientific evidence is more difficult due to a number of factors. The goal of this chapter is to discuss how to estab...
IOP Conference Series: Earth and Environmental Science, 2018
Primary dysmenorrhea is a gynecological disorder which most commonly occurs like a pain in the in... more Primary dysmenorrhea is a gynecological disorder which most commonly occurs like a pain in the initial menstruation. One ofthe attempts to handle dysmenorrhea is by using anon-pharmacological method such as herbal therapy which uses red ginger. The research was at Akbid and Akper Harapan Mama, Deli Serdang Regency, with pre-experimental design and one group pretest-posttest. The samples were 32 female students as the respondents, taken by using non-probability or consecutive sampling technique. PGF2a content measurement by ELISA, theintensity of pain by Visual Analogue Scale and analyzed by using Wilcoxon test. PGF2α content before giving red ginger capsule supplement median was 156.50 pg/ml (min-max: 57-1037 pg/ml), after giving it was 101 (min-max: 22-785), pain intensity before giving it in the mean score of 2 was 15 respondents (47%), after giving it in the mean score of 0 was 14 respondents (44%). The result of statistic test on PGF2α content before and after giving it was p-value = 0.001, and pain intensity before and after giving it was p < 0.001 which indicated that there was asignificant decrease in PGF2α and pain intensity after giving it. Red ginger capsule supplement could decrease PGF2α content during primary dysmenorrhea.
BACKGROUND: Interleukin (IL)-31 serum levels were significantly higher in hemodialysis patients w... more BACKGROUND: Interleukin (IL)-31 serum levels were significantly higher in hemodialysis patients with pruritus, whereas acupuncture in LI11 was shown to improve symptoms of pruritus. However, there is limited information that IL-31 serum levels that correlate with decreased dimensions of the pruritus after acupuncture in LI11 in a hemodialysis patient. AIM: The aim of the study was to demonstrate the impact of acupuncture in LI11 and IL-31 serum level and its correlation with dimensions of the pruritus in hemodialysis patients. METHODS: A randomized clinical trial has been carried out from August 2019 to December 2019 at H. Adam Malik General Hospital, Medan, Indonesia. Sixty patients underwent hemodialysis who were randomly allocated to two groups, one group got acupuncture in Quchi LI11 (intervention group), and the other group got a placebo (control group). IL-31 serum levels and pruritus were measured before and after 6 weeks of acupuncture in both groups. RESULTS: Acupuncture di...
Open Access Macedonian Journal of Medical Sciences, 2020
BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Maligna... more BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Malignancy is one of the most common causes of death in the world. T2DM is one of the risk factors for malignancy. This is caused by an increase in blood glucose levels (hyperglycemia) which will cause tissue hypoxia which can lead to malignancy. The cell adaptation response to hypoxia is relaxed by a marker called hypoxia-inducible factor-1 alpha (HIF-1α), where a condition converts hyperglycemia to a loss of cellular response to hypoxia in most complications of diabetes. AIM: The aim of this study was to determine level HIF-1α at T2DM with malignancy, where this study used the samples of the T2DM patients with malignancy and T2DM without malignancy. METHODS: The cross-sectional study design used the 89 samples of DM patients with and without malignancy who attended Murni Teguh Hospital in Medan of Indonesia country. The inclusion criteria of the samples were all the patients diagnosed with T2...
Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most ... more Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most recent best evidence, is gaining popularity. Individual clinical expertise is combined with the best available external clinical evidence derived from systematic research in the practice of EBM. The key and core of EBM is the hierarchical system for categorizing evidence. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system divides evidence quality into four categories: high, moderate, low, and very low. GRADE is based on the lowest quality of evidence for any of the outcomes that are critical to making a decision, reducing the risk of mislabeling the overall evidence quality, when evidence for a critical outcome is lacking. This principle is also used in acupuncture as a complementary and integrative treatment modality, but incorporating scientific evidence is more difficult due to a number of factors. The goal of this chapter is to discuss how to estab...
Background : The increasing prevalence of obesity is a major health problem worldwide. About 2.8 ... more Background : The increasing prevalence of obesity is a major health problem worldwide. About 2.8 million adults die each year linked to overweight and obesity. Individuals with overweight and obesity will experience an increased risk for health conditions. Several recent epidemiological studies have shown that obesity is associated with Chronic Kidney Disease (PGK). Method : This study aims to determine the description of Creatinine in Adult Obesity In Pasar 2 Tanjung Sari Medan 2017. This research is a descriptive study with cross sectional approach. Data collected from measurements of weight, height and plasma creatinine. Population in this study is all obese subject in the market 2 tanjung sari where the number of amps of 36 people. Results : High creatinine from normal age by age 30-39, 40-49 years and> 50 years each of 1 person. High creatinine from normal by sex is more common in men as many as 2 people, followed by women as much as 1 person. Creatinine is higher than norma...
BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Maligna... more BACKGROUND: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide. Malignancy is one of the most common causes of death in the world. T2DM is one of the risk factors for malignancy. This is caused by an increase in blood glucose levels (hyperglycemia) which will cause tissue hypoxia which can lead to malignancy. The cell adaptation response to hypoxia is relaxed by a marker called hypoxia-inducible factor-1 alpha (HIF-1α), where a condition converts hyperglycemia to a loss of cellular response to hypoxia in most complications of diabetes. AIM: The aim of this study was to determine level HIF-1α at T2DM with malignancy, where this study used the samples of the T2DM patients with malignancy and T2DM without malignancy. METHODS: The cross-sectional study design used the 89 samples of DM patients with and without malignancy who attended Murni Teguh Hospital in Medan of Indonesia country. The inclusion criteria of the samples were all the patients diagnosed with T2...
Asma merupakan gangguan inflamasi kronik pada sistem pernafasan. Terjadi inflamasi yang khas kare... more Asma merupakan gangguan inflamasi kronik pada sistem pernafasan. Terjadi inflamasi yang khas karena disertai infiltrasi eosinofil, hal ini membedakan asma dari gangguan inflamasi jalan napas lainnya. Eosinofil merupakan mediator inflamasi utama pada asma. Eosinofil merangsang produksi mediator inflamasi, sitokin dan mediator. Pemahaman efek eosinofil menjadi dasar terapi asma, yaitu dengan menghambat sitokin, eosinofil dan menghambat interaksi antara eosinofil dan sel endotel. Selain itu menjadi dasar pengembangan modalitas terapi asma seperti Cyklophilin, Antibodi monoklonal antihuman IL-5, Anti Interleukin-1, Interleukin 10, Interleukin 12 dan Antihistamin. Pengetahuan ini memberi pemahaman mekanisme obat yang lazim digunakan seperti Glucocorticoid dan Anti leukotrine
Latar belakang: Buah Kurma selama ini masih menjadi suatu pertanyaan apakah dapat dikonsumsi oleh... more Latar belakang: Buah Kurma selama ini masih menjadi suatu pertanyaan apakah dapat dikonsumsi oleh penderita diabetes melitus tipe-2 yang terkontrol (diabetesi), tanpa mengacaukan kontrol glukosa darah (KGD). Tujuan: Untuk mengetahui perubahan KGD diabetesi setelah mengkonsumsi kurma. Bahan Dan Cara: Diteliti secara Uji klinis menyilang terhadap 36 orang diabetisi pria 22 orang dan wanita 14 orang dengan umur rata-rata 60±5,5 tahun, memakai Obat Hipoglikemik Oral (OHO) 28 orang dan Insulin 8 orang. Penelitian dilakukan 2 kali perlakuan, perlakuan-I, 18 orang mendapat 3 buah kurma dan 18 orang mendapat 1 buah pisang, KGD diukur sebelum memakan dan sesudah memakan masing-masing buah. Perlakuan-II seminggu kemudian kelompok yang sebelumnya mendapat 3 biji kurma diberikan 1 buah pisang dan begitu sebaliknya dan diukur KGD sebelum dan 2 jam sesudah memakan masing-masing buah. Hasil: Pada perlakuan-I Tidak ada perbedaan KGD sebelum menkonsumsi kurma dan 2 jam sesudah mengkonsumsi kurma (12...
The capacity of physical ability can be improved through doing an exercise which is according to ... more The capacity of physical ability can be improved through doing an exercise which is according to the intensity, duration and frequency. Exercise can improve the immunity system and influence the leucocyte. The number of pheripheral leucocyte can be the resource of information for the diagnostics and prognose the description of organ damage and the recovery after physical training. The purpose of this study to investigate the influence of moderate physical activity (MPA) to leucocyte count and diffrential leucocyte. This study is experimental with pretest-posttest group design. The subjects for this study is a women who are between 18-20 years old, they were 15 person. The subjects of study were given moderate intensity of physical activity in the form of stepping up and down test until the reached the targeted heartbeats which is 80% of the maximum heartbeats. The physical activity was done for a moment. Before doing the activity, the pheripheral blood was taken once, then the blood...
Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most ... more Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most recent best evidence, is gaining popularity. Individual clinical expertise is combined with the best available external clinical evidence derived from systematic research in the practice of EBM. The key and core of EBM is the hierarchical system for categorizing evidence. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system divides evidence quality into four categories: high, moderate, low, and very low. GRADE is based on the lowest quality of evidence for any of the outcomes that are critical to making a decision, reducing the risk of mislabeling the overall evidence quality, when evidence for a critical outcome is lacking. This principle is also used in acupuncture as a complementary and integrative treatment modality, but incorporating scientific evidence is more difficult due to a number of factors. The goal of this chapter is to discuss how to establish a clinical evidence system for acupuncture, with a focus on the current quality of evidence for a variety of conditions or diseases.
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