... adult female Mariam Saeed, Nadia Ali Azfar, Tariq Zaman*, Mohammad Jahangir Department of Dermatology, Allama Iqbal Medical College/Jinnah Hospital, Lahore *Department of Dermatology, FMH College of Medicine &... more
... adult female Mariam Saeed, Nadia Ali Azfar, Tariq Zaman*, Mohammad Jahangir Department of Dermatology, Allama Iqbal Medical College/Jinnah Hospital, Lahore *Department of Dermatology, FMH College of Medicine & Dentistry, Lahore ...
Research Interests:
Research Interests:
Indigenous knowledge is held locally in the memories and practices of the communities. The communities have their own processes of storage, leverage, practice, share, and developing indigenous knowledge. The form of knowledge management... more
Indigenous knowledge is held locally in the memories and practices of the communities. The communities have their own processes of storage, leverage, practice, share, and developing indigenous knowledge. The form of knowledge management (KM) employed however distinctly differs from the current practices in organizations. The paper focuses on this less studied, but potentially invaluable, indigenous knowledge management (IKM) practices within these indigenous communities. The Balanced Scorecard (BSC) is a strategic ...
Research Interests: Knowledge Management, Performance Management, Strategic Planning, Indigenous Knowledge, Balanced Scorecard, and 12 moreIndigenous ecological knowledges and practices, Multidisciplinary, Indigenous knowledge systems, KPI, Knowledge Management System, Indigenous Communities, Balance Scorecard, Metric, PDCA, Holistic Approach, Knowledge Management for Development, and Performance Measure
Pakistan has a large population of more than 150 million people with an overall carrier frequency of approximately 5.6% for β-thalassemia. Punjab is the largest province of the country having more than 50% of the population. The state of... more
Pakistan has a large population of more than 150 million people with an overall carrier frequency of approximately 5.6% for β-thalassemia. Punjab is the largest province of the country having more than 50% of the population. The state of β-thalassemia is alarming as consanguinity is very high (>81%) and the literacy rate is low in South Punjab. A thalassemia prevention program is the need of the hour in this part of Pakistan. In this study, we initiated awareness, screening, and characterization of the mutations causing β-thalassemia as well as a genetic counseling program mainly in the districts of Faisalabad and D.G. Khan to establish prenatal diagnosis, a facility previously unavailable in this region for disease prevention. A total of 248 unrelated transfusion-dependent children and the available members of their families were screened to characterize the mutations and identify the carriers. Genetic counseling was provided to these families and prenatal diagnosis offered. In the samples analyzed, 11 β-thalassemia mutations and three hemoglobin variants were detected mainly by using the Monoplex and Multiplex ARMS-PCR. First-trimester prenatal diagnosis was carried out through chorionic villus sampling (CVS) in seven pregnancies at risk. As a result of our campaign, 145 carrier couples planning to have more children gave their consent to have retrospective prenatal diagnosis in every pregnancy in future. A cooperative trend and a positive attitude toward the prevention of β-thalassemia were noticed in the families with affected children and in the general population. Copyright © 2006 John Wiley & Sons, Ltd.