jose cobo

ABSTRACT The paper deals with the calculation of the 3D harmonic lambda modes in a B.W.R. reactor. An algorithm to calculate the harmonic lambda modes corresponding to the steady state two-group 3D neutron-diffusion equation is presented. The algorithm uses subspace iteration method techniques combined with convergence acceleration based on variational principles. The methodology has been tested on two benchmark problems, and applied to obtain the 3D modes of the Cofrentes Nuclear Power Plant.

Different lactic acid bacteria have often been administered as a dietary means to enhance immune system activity. Based on this statement, the aim of the current work was to test the effects of a Lactobacillus casei DN114001 fermented milk consumption on the immune response capacity in middle-age volunteers. Forty-five healthy volunteers, 24 women and 21 men (aged: 51–58 years), were randomized into two groups to receive three cups per day of a L. casei DN114001 (108–1010 ufc/g) fermented milk (n=23), or placebo (n=22), during an 8-week period. Measurements were performed before (day 0), and after the nutritional intervention (day 56). After the trial, no changes in immune cell proportions were detected, but the probiotic-treated group increased oxidative burst capacity of monocytes (probiotic group: p=0.029; placebo group: p=0.625), as well as NK cells tumoricidal activity (probiotic group: p=0.023; placebo group: p=0.125). Results showed that daily intake of fermented milk containing Lactobacillus casei DN114001 could have a positive effect in modulating the innate immune defense in healthy-middle-age people. El consumo de ciertas cepas de bacterias acidolácticas podría ser beneficioso para la actividad del sistema immune. El objetivo del presente trabajo consistió en verificar dichos efectos tras consumo de leche fermentada conteniendo Lactobacillus casei DN114001. En el estudio participaron 45 voluntarios sanos, 23 mujeres y 22 hombres, de edad entre 51 y 58 años. Durante 8 semanas, los sujetos consumieron 3 unidades al día del producto que les fue asignado de manera aleatoria: leche fermentada (n=23) con L. casei DN114001 (108–1010 ufc/g), o leche no fermentada a modo de placebo (n=22). Las determinaciones en muestras sanguíneas se realizaron al inicio (día 0) y al final del ensayo (día 56). Tras el período de intervención nutricional, el grupo que consumió el probiótico incrementó significativamente la capacidad oxidativa de los monocitos (probiótico: p=0.029; placebo: =0.625), y la capacidad tumoricida de las células NK (probiótico: p=0.023; placebo: =0.123). Estos resultados sugieren que el consumo regular de leche fermentada con presencia de Lactobacillus casei DN114001 podría potenciar la inmunidad innata en personas de mediana edad.