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Research Interests:
Research Interests:
Research Interests:
Research Interests: Engineering, Computer Science, Algorithms, Artificial Intelligence, Medicine, and 15 moreElectrocardiography, Knowledge Based System, Humans, Heart rate, Knowledge base, High performance, Sliding Window, Arrhythmia, Sensitivity and Specificity, Classification Algorithm, Predictive value of tests, Ventricular Fibrillation, Bundle Branch Block, Databases as topic, and signal extraction
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Research Interests:
To study the efficacy and safety of vibrational angioplasty versus hydrophilic guidewires for recanalizing chronic total occlusions (CTOs) of the coronary arteries. In a retrospective study, 99 patients with old (>3 months) CTOs... more
To study the efficacy and safety of vibrational angioplasty versus hydrophilic guidewires for recanalizing chronic total occlusions (CTOs) of the coronary arteries. In a retrospective study, 99 patients with old (>3 months) CTOs resistant to conventional techniques were treated either with vibrational angioplasty (group A, n = 72) or 0.014-inch hydrophilic guidewires (group B, n = 27). The selection of the technique (vibrational angioplasty or hydrophylic guidewires) was dependent only upon device availability. A variety of guidewires were employed in conjunction with vibrational angioplasty. The crossing success rates in groups A and B were 86.1% (62/72) and 55.5% (15/27) (p < 0.05), with final procedural success rates of 75% (54/72) and 44.4% (12/27) (p < 0.01), respectively. The main reasons for failure were inability to cross the lesion with a guidewire (10/18 in group A and 12/15 in group B) and large dissections resulting in vessel closure (2/18 in group A and 2/15 in group B). Three major complications were seen, 2 in group A and 1 in group B. Three vessel perforations were reported in group A. Both techniques needed prolonged fluoroscopy times. Vibrational angioplasty was more successful in treating CTOs compared to hydrophilic guidewires and had similar complication rates (most without clinical sequelae).
Research Interests: Surgery, Treatment Outcome, Medicine, Endovascular Therapy, Complication, and 15 moreHumans, Chronic Disease, Female, Fluoroscopy, Male, Clinical Sciences, Angioplasty, Aged, Middle Aged, Coronary Angiography, Adult, Coronary heart disease, Retrospective Studies, Postoperative Complications, and Intraoperative complications
Research Interests: Cardiology, Cardiovascular, Nuclear medicine, Histology, Comparative Study, and 15 moreMedicine, Models, Sheep, Animals, Male, Technique, Artery, Behavioral Animal Models, In Vivo, Peripheral Vascular Disease, Equipment Design, Coronary artery, Vascular Disease, Cardiovascular medicine and haematology, and Coronary Vessels
Research Interests: Endocrinology, Biology, Medicine, Apolipoproteins, Humans, and 15 moreInternal Medicine, Blood Glucose, Diabetes mellitus, Cholesterol, Female, Male, Apolipoprotein B, Clinical Sciences, High Resolution, Family Health, Biological markers, Lipoprotein a, Glycaemic control, Cardiovascular medicine and haematology, and Paediatrics and reproductive medicine
Research Interests: Epidemiology, Incidence Geometry, Cardiovascular disease, Medicine, Greece, and 15 morePopulation, Humans, Internal Medicine, Female, Male, Atrial Fibrillation, Incidence, Clinical Sciences, Aged, Middle Aged, Adult, Arrhythmia, Epidemiologic Studies, General Population, and Paroxysmal atrial fibrillation
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Research Interests:
Research Interests:
Purpose: To study the dose and time effect of external beam irradiation on the morphometry of both angioplasted and nonangioplasted arteries in a hypercholesterolemic rabbit model. Methods and materials: Eight groups of rabbit femoral... more
Purpose: To study the dose and time effect of external beam irradiation on the morphometry of both angioplasted and nonangioplasted arteries in a hypercholesterolemic rabbit model. Methods and materials: Eight groups of rabbit femoral arteries were studied: arteries (a) with no intervention, (b) irradiated with a 12-Gy 6 MV X-ray dose, (c) with a 18-Gy, (d) treated with balloon angioplasty,
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Purpose: To study the dose and time effect of external beam irradiation on the morphometry of both angioplasted and nonangioplasted arteries in a hypercholesterolemic rabbit model. Methods and materials: Eight groups of rabbit femoral... more
Purpose: To study the dose and time effect of external beam irradiation on the morphometry of both angioplasted and nonangioplasted arteries in a hypercholesterolemic rabbit model. Methods and materials: Eight groups of rabbit femoral arteries were studied: arteries (a) with no intervention, (b) irradiated with a 12-Gy 6 MV X-ray dose, (c) with a 18-Gy, (d) treated with balloon angioplasty,
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Research Interests:
Objective: Platelet activation and aggregation is a dominant feature in the pathophysiology of unstable angina. The final step of platelet aggregation is mediated through the platelet integrin glycoprotein IIb/IIIa (GP IIb/IIIa), while... more
Objective: Platelet activation and aggregation is a dominant feature in the pathophysiology of unstable angina. The final step of platelet aggregation is mediated through the platelet integrin glycoprotein IIb/IIIa (GP IIb/IIIa), while abciximab (ReoPro) is one of the most potent ...
Research Interests: Cardiovascular, Treatment, Platelet, Humans, Platelet aggregation, and 15 moreCholesterol, Female, Male, Monoclonal Antibodies, Platelet activation mechanism, Triglycerides, Aged, Middle Aged, Platelet Rich Plasma, Analysis of Variance, Enzyme activity, Lipoprotein a, Case Control Studies, Platelet Aggregation Inhibitors, and Cardiovascular medicine and haematology
The effect of acute changes in ventricular pressure is examined on the QRS duration to clarify the mechanism of ventricular pressure-related arrhythmogenesis. Ventricular pressure was changed acutely by arterial transfusion-bleeding into... more
The effect of acute changes in ventricular pressure is examined on the QRS duration to clarify the mechanism of ventricular pressure-related arrhythmogenesis. Ventricular pressure was changed acutely by arterial transfusion-bleeding into an open-air ventricular pressure reservoir that ...
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Research Interests: Epidemiology, Humans, Epinephrine, Hemodynamics, Blood Pressure, and 15 moreFemale, Male, Cohort Study, Heart, Arterial Blood Pressure, Left Ventricular Dysfunction, Norepinephrine, Middle Aged, Coronary Artery Disease, Ejection Fraction, Left Ventricular Function, Catecholamines, Cohort Studies, Systolic blood pressure, and Cardiovascular medicine and haematology
Research Interests:
1. J Electrocardiol. 1995 Apr;28(2):147-52. Effect of preload and afterload on ventricular arrhythmogenesis. Sideris DA, Pappas S, Siongas K, Grekas G, Argyri-Greka O, Koundouris E, Foussas S. Department of Internal Medicine, Medical... more
1. J Electrocardiol. 1995 Apr;28(2):147-52. Effect of preload and afterload on ventricular arrhythmogenesis. Sideris DA, Pappas S, Siongas K, Grekas G, Argyri-Greka O, Koundouris E, Foussas S. Department of Internal Medicine, Medical School of Ioannina University, Greece. ...