We analysed the renal artery wall using serial high resolution CT image analysis before and at 6 ... more We analysed the renal artery wall using serial high resolution CT image analysis before and at 6 months after renal artery denervation in the EnligHTN 1 trial. The EnligHTN-I study was a prospective, multi-center, non-randomized study to evaluate the clinical efficacy of the EnligHTN multi-electrode radiofrequency ablation catheter in resistant hypertensive patients. 40 patients with serial renal artery CT imaging were analyzed. Cross-sectional images of renal arteries at 1-mm interval were acquired by a commercially available software (3-mensio, Structural heart, ver 5.1). The luminal and outer wall boundaries of renal arteries were manually traced at 1 mm interval. Total atheroma volume (TAV) was calculated by summation of the plaque area which was the difference between the lumen and vessel wall areas. Percent atheroma volume (PAV) was calculated as the proportion of vessel wall volume occupied by plaque volume. On serial evaluation, greater progression of PAV and TAV was observe...
We analysed the renal artery wall using serial high resolution CT image analysis before and at 6 ... more We analysed the renal artery wall using serial high resolution CT image analysis before and at 6 months after renal artery denervation in the EnligHTN 1 trial. The EnligHTN-I study was a prospective, multi-center, non-randomized study to evaluate the clinical efficacy of the EnligHTN multi-electrode radiofrequency ablation catheter in resistant hypertensive patients. 40 patients with serial renal artery CT imaging were analyzed. Cross-sectional images of renal arteries at 1-mm interval were acquired by a commercially available software (3-mensio, Structural heart, ver 5.1). The luminal and outer wall boundaries of renal arteries were manually traced at 1 mm interval. Total atheroma volume (TAV) was calculated by summation of the plaque area which was the difference between the lumen and vessel wall areas. Percent atheroma volume (PAV) was calculated as the proportion of vessel wall volume occupied by plaque volume. On serial evaluation, greater progression of PAV and TAV was observe...
Uploads