Objective: The research was conducted to identify the factors influencing social adaptation to th... more Objective: The research was conducted to identify the factors influencing social adaptation to the disease in the COVID-19 pandemic. Material and Methods: The cross-sectional study was carried out prospectively in a pandemic hospital in Istanbul between 10 May 2020 and 30 May 2020 after obtaining the permission of the Ministry of Health COVID-19 Scientific Research Evaluation Commission, institutional permission and ethics committee permission, with 100 patients who accepted to participate in the study who received inpatient treatment due to COVID-19. A patient information form, which includes demographic information, and the Psychosocial Self-Adjustment to Illness Scale were administered to the patients. Results: The mean age of patients participating in the study was 45.74±17.27 years, 49% were female, 63% were married, 25% had completed primary school, and 41% were not working. The mean psychosocial adjustment score of individuals with COVID-19 was 39.27±19.53. Conclusion: COVID-...
BACKGROUND SARS-COV-2 virus that causes COVID-19 binds to the host cell with angiotensin converti... more BACKGROUND SARS-COV-2 virus that causes COVID-19 binds to the host cell with angiotensin converting enzyme-2 causing acute respiratory distress syndrome (ARDS) and severe mortality and morbidity. There are studies in the literature conducted on the importance of serum angiotensin converting enzyme (ACE) and ACE-2 enzymes in ARDS pathogenesis. Serum ACE levels are higher in children and adolescents than in adults, and COVID-19 has a milder progression. All these reasons suggest that there may be a relationship between serum ACE levels and COVID-19 prognosis. METHODS The serum ACE levels were determined at the time of hospitalization due to COVID-19 diagnosis in this single-centered, prospective study. According to discharge status, patients were divided into three groups as "Discharge with Healing", "Intensive Care Need" and "Mortality", and the effect of serum ACE levels on disease prognosis was investigated. RESULTS The present study comprised a total ...
Background and study aims The Coronavirus Disease 2019 (COVID-19) epidemic especially worries peo... more Background and study aims The Coronavirus Disease 2019 (COVID-19) epidemic especially worries people with chronic diseases the entire world. In this study, the frequency, and clinical course of COVID-19 infection in patients with Celiac disease (CD) were investigated. CD patients' adherence to purchasing gluten free products (GFPs), the strict diet, and how patients' anxiety affects CD symptoms during the COVID-19 outbreak were also examined. Patients and methods A detailed questionnaire was administered by telephone and emailed to the CD patients to determine the status of these patients in obtaining GFPs, and dietary compliance during the COVID-19 pandemic. State and trait anxiety levels of patients were evaluated using the State-trait Anxiety Inventory (STAI) scale. Additionally, whether patients with CD were diagnosed with COVID-19, and if diagnosed, their clinical course of the disease were investigated. Results One hundred and one patients were included in the study. T...
There are controversial suggestions in the literature about the routine measurement of calcitonin... more There are controversial suggestions in the literature about the routine measurement of calcitonin (Ct) in thyroid nodules. Barriers in front of measuring routine serum calcitonin are cost-effectiveness and the possibility of having elevated serum Ct in the absence of medullary thyroid carcinoma (MTC). Here we report a sporadic MTC patient with negative fine needle aspiration biopsy (FNAB) result whose diagnosis was made by preoperative calcitonin measurement. As we perform routine Ct measurement before surgery, the surgeon becomes aware of the MTC earlier, and this gives the opportunity of making an appropriate surgical procedure which is crucial for patients’ outcome.
Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome ... more Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome have not been well-defined yet. The aim of this study is to delineate the prognostic importance of presence of concomitant cardiac injury on admission in patients with COVID-19. Methods For this multi-center retrospective study, data of consecutive patients who were treated for COVID-19 between 20 March and 20 April 2020 were collected. Clinical characteristics, laboratory findings and outcomes data were obtained from electronic medical records. In-hospital clinical outcome was compared between patients with and without cardiac injury. Results A total of 607 hospitalized patients with COVID-19 were included in the study; the median age was 62.5 ± 14.3 years, and 334 (55%) were male. Cardiac injury was detected in 150 (24.7%) of patients included in the study. Mortality rate was higher in patients with cardiac injury (42% vs. 8%; P < 0.01). The frequency of patients who required ICU (7...
The purpose of the study was to compare serum visfatin levels between patients with acromegaly an... more The purpose of the study was to compare serum visfatin levels between patients with acromegaly and healthy controls and to evaluate the relationships between visfatin levels and epicardial fat thickness (EFT), carotid intima media thickness (cIMT), and ankle brachial index (ABI). We conducted a cross-sectional case-control study of 54 patients with acromegaly (37 females and 17 males) and 34 healthy controls (22 females and 12 males). Serum visfatin was measured by ELISA. Acromegalic and control participants and those with active or controlled acromegaly were compared with respect to their serum visfatin, clinical and metabolic parameters, EFT, cIMT, and ABI. Linear correlation was used to identify associations between these parameters and visfatin in all participants. Serum visfatin and glycated hemoglobin (HbA1c) were higher in the acromegaly group than in the control group (p<0.001 and p=0.007, respectively). There was no difference in visfatin between the active and controlle...
Experimental and Clinical Endocrinology & Diabetes, 2018
Background Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disorder. Bo... more Background Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disorder. Both neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are reported to be increased in various inflammation-related diseases, but their clinical significance in HT remains unclear. Objectives The aim of this study was to investigate the relationship between thyroid autommunity and NLR and PLR as markers of systemic inflammation in HT. Methods In this study, we evaluated 145 women with HT and 60 age-matched healthy controls. We compared the PLR and the NLR of HT patients with controls and the correlation between the NLR, PLR, and C-reactive protein (CRP), thyroid-stimulating hormone (TSH) and thyroid antibody titers in the patient group. Also we compared the PLR and the NLR of HT patients that received levothyroxine with those who did not receive levothyroxine Results There were no significant differences between patient and control groups in terms of overall leuko...
Objective: The research was conducted to identify the factors influencing social adaptation to th... more Objective: The research was conducted to identify the factors influencing social adaptation to the disease in the COVID-19 pandemic. Material and Methods: The cross-sectional study was carried out prospectively in a pandemic hospital in Istanbul between 10 May 2020 and 30 May 2020 after obtaining the permission of the Ministry of Health COVID-19 Scientific Research Evaluation Commission, institutional permission and ethics committee permission, with 100 patients who accepted to participate in the study who received inpatient treatment due to COVID-19. A patient information form, which includes demographic information, and the Psychosocial Self-Adjustment to Illness Scale were administered to the patients. Results: The mean age of patients participating in the study was 45.74±17.27 years, 49% were female, 63% were married, 25% had completed primary school, and 41% were not working. The mean psychosocial adjustment score of individuals with COVID-19 was 39.27±19.53. Conclusion: COVID-...
BACKGROUND SARS-COV-2 virus that causes COVID-19 binds to the host cell with angiotensin converti... more BACKGROUND SARS-COV-2 virus that causes COVID-19 binds to the host cell with angiotensin converting enzyme-2 causing acute respiratory distress syndrome (ARDS) and severe mortality and morbidity. There are studies in the literature conducted on the importance of serum angiotensin converting enzyme (ACE) and ACE-2 enzymes in ARDS pathogenesis. Serum ACE levels are higher in children and adolescents than in adults, and COVID-19 has a milder progression. All these reasons suggest that there may be a relationship between serum ACE levels and COVID-19 prognosis. METHODS The serum ACE levels were determined at the time of hospitalization due to COVID-19 diagnosis in this single-centered, prospective study. According to discharge status, patients were divided into three groups as "Discharge with Healing", "Intensive Care Need" and "Mortality", and the effect of serum ACE levels on disease prognosis was investigated. RESULTS The present study comprised a total ...
Background and study aims The Coronavirus Disease 2019 (COVID-19) epidemic especially worries peo... more Background and study aims The Coronavirus Disease 2019 (COVID-19) epidemic especially worries people with chronic diseases the entire world. In this study, the frequency, and clinical course of COVID-19 infection in patients with Celiac disease (CD) were investigated. CD patients' adherence to purchasing gluten free products (GFPs), the strict diet, and how patients' anxiety affects CD symptoms during the COVID-19 outbreak were also examined. Patients and methods A detailed questionnaire was administered by telephone and emailed to the CD patients to determine the status of these patients in obtaining GFPs, and dietary compliance during the COVID-19 pandemic. State and trait anxiety levels of patients were evaluated using the State-trait Anxiety Inventory (STAI) scale. Additionally, whether patients with CD were diagnosed with COVID-19, and if diagnosed, their clinical course of the disease were investigated. Results One hundred and one patients were included in the study. T...
There are controversial suggestions in the literature about the routine measurement of calcitonin... more There are controversial suggestions in the literature about the routine measurement of calcitonin (Ct) in thyroid nodules. Barriers in front of measuring routine serum calcitonin are cost-effectiveness and the possibility of having elevated serum Ct in the absence of medullary thyroid carcinoma (MTC). Here we report a sporadic MTC patient with negative fine needle aspiration biopsy (FNAB) result whose diagnosis was made by preoperative calcitonin measurement. As we perform routine Ct measurement before surgery, the surgeon becomes aware of the MTC earlier, and this gives the opportunity of making an appropriate surgical procedure which is crucial for patients’ outcome.
Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome ... more Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome have not been well-defined yet. The aim of this study is to delineate the prognostic importance of presence of concomitant cardiac injury on admission in patients with COVID-19. Methods For this multi-center retrospective study, data of consecutive patients who were treated for COVID-19 between 20 March and 20 April 2020 were collected. Clinical characteristics, laboratory findings and outcomes data were obtained from electronic medical records. In-hospital clinical outcome was compared between patients with and without cardiac injury. Results A total of 607 hospitalized patients with COVID-19 were included in the study; the median age was 62.5 ± 14.3 years, and 334 (55%) were male. Cardiac injury was detected in 150 (24.7%) of patients included in the study. Mortality rate was higher in patients with cardiac injury (42% vs. 8%; P < 0.01). The frequency of patients who required ICU (7...
The purpose of the study was to compare serum visfatin levels between patients with acromegaly an... more The purpose of the study was to compare serum visfatin levels between patients with acromegaly and healthy controls and to evaluate the relationships between visfatin levels and epicardial fat thickness (EFT), carotid intima media thickness (cIMT), and ankle brachial index (ABI). We conducted a cross-sectional case-control study of 54 patients with acromegaly (37 females and 17 males) and 34 healthy controls (22 females and 12 males). Serum visfatin was measured by ELISA. Acromegalic and control participants and those with active or controlled acromegaly were compared with respect to their serum visfatin, clinical and metabolic parameters, EFT, cIMT, and ABI. Linear correlation was used to identify associations between these parameters and visfatin in all participants. Serum visfatin and glycated hemoglobin (HbA1c) were higher in the acromegaly group than in the control group (p<0.001 and p=0.007, respectively). There was no difference in visfatin between the active and controlle...
Experimental and Clinical Endocrinology & Diabetes, 2018
Background Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disorder. Bo... more Background Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disorder. Both neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are reported to be increased in various inflammation-related diseases, but their clinical significance in HT remains unclear. Objectives The aim of this study was to investigate the relationship between thyroid autommunity and NLR and PLR as markers of systemic inflammation in HT. Methods In this study, we evaluated 145 women with HT and 60 age-matched healthy controls. We compared the PLR and the NLR of HT patients with controls and the correlation between the NLR, PLR, and C-reactive protein (CRP), thyroid-stimulating hormone (TSH) and thyroid antibody titers in the patient group. Also we compared the PLR and the NLR of HT patients that received levothyroxine with those who did not receive levothyroxine Results There were no significant differences between patient and control groups in terms of overall leuko...
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