Statins modify inflammatory cell signaling during the immune response to infection. This has been... more Statins modify inflammatory cell signaling during the immune response to infection. This has been considered as a pleotropic effect. Effects of statins in inflammatory conditions such as bacteremia have been found to be controversial. We examined the effect of statins on the mortality of bacteremia patients. Major databases were searched for the pertinent clinical trials. Six cohort studies comprising 7553 patients were included. Hospital mortality was lower (15.36% vs 22.28%) in patients on statin. There may be a potential role of statins in similar inflammatory and infective conditions.
Statins modify inflammatory cell signaling during the immune response to infection. This has been... more Statins modify inflammatory cell signaling during the immune response to infection. This has been considered as a pleotropic effect. Effects of statins in inflammatory conditions such as bacteremia have been found to be controversial. We examined the effect of statins on the mortality of bacteremia patients. Major databases were searched for the pertinent clinical trials. Six cohort studies comprising 7553 patients were included. Hospital mortality was lower (15.36% vs 22.28%) in patients on statin. There may be a potential role of statins in similar inflammatory and infective conditions.
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Papers by Maryam Mahmood