Drug reaction with eosinophilia and systemic symptom (DRESS) is a severe drug-induced cutaneous reaction with visceral involvement and blood abnormalities associated with reactivations of herpes-virus family i.e., EBV, HHV-6, HHV-7 and... more
Drug reaction with eosinophilia and systemic symptom (DRESS) is a severe drug-induced cutaneous reaction with visceral involvement and blood abnormalities associated with reactivations of herpes-virus family i.e., EBV, HHV-6, HHV-7 and CMV. Recently, we demonstrated that the immune response in DRESS, previously thought to be directed only against drug components, is also mediated by herpes-virus specific cytotoxic CD8+ T lymphocytes which home to the skin and visceral organs.
Our results suggest a new role for drugs in the pathogenesis of DRESS that could enhanced the immune response in vivo.
Our results suggest a new role for drugs in the pathogenesis of DRESS that could enhanced the immune response in vivo.
