The azimuthal variation of jet yields in heavy-ion collisions provides information about the path-length dependence of the energy loss experienced by partons passing through the hot, dense nuclear matter known as the quark-gluon plasma.... more
The azimuthal variation of jet yields in heavy-ion collisions provides information about the path-length dependence of the energy loss experienced by partons passing through the hot, dense nuclear matter known as the quark-gluon plasma. This paper presents the azimuthal anisotropy coefficients $v_2$, $v_3$, and $v_4$ measured for jets in Pb+Pb collisions at $\sqrt{s_{NN}} =$ 5.02 TeV using the ATLAS detector at the LHC. The measurement uses data collected in 2015 and 2018, corresponding to an integrated luminosity of 2.2 nb$^{-1}$. The $v_n$ values are measured as a function of the transverse momentum of the jets between 71 GeV and 398 GeV and the event centrality. A nonzero value of $v_2$ is observed in all but the most central collisions. The value of $v_2$ is largest for jets with lower transverse momentum, with values up to 0.05 in mid-central collisions. A smaller, nonzero value of $v_3$ of approximately 0.01 is measured with no significant dependence on jet $p_T$ or centrality...
Research Interests:
Research Interests:
A new labelling approach of haptenic drugs with digoxigenin for the development of competitive enzyme immunoassay (EIA) is reported. It consists of the covalent linking of the hapten to the preactivated digoxigenin derivative and... more
A new labelling approach of haptenic drugs with digoxigenin for the development of competitive enzyme immunoassay (EIA) is reported. It consists of the covalent linking of the hapten to the preactivated digoxigenin derivative and revealing the immune complexes with anti-digoxigenin Fab fragments coupled to alkaline phosphatase. This approach has been applied to the development of an EIA for the pharmacokinetic study of lesopitron (E-4424), a new anxiolytic agent. The assay involves a solid-phase immobilization of IgG purified from polyclonal antiserum developed against the butylamino derivative of lesopitron covalently linked to bovine serum albumin. The tracer consists of the covalent linking of the same butylamino derivative to digoxigenin-3-O-methylcarbonyl-epsilon-aminocaproic acid N-hydroxysuccinimide ester. The calibration curve for E-4424 from 12.5 to 6400 pg per well displays an ED50 of 34.5 pg per well, a slope factor of 0.86 and a minimum detectable dose of 4.1 pg per well. The accuracy and the precision of the assay assessed at three different concentrations of E-4424 (500, 1000 and 2000 pg ml-1) give a recovery higher than 95% and intra- and inter-assay RSDs lower than 5 and 10%, respectively. The specificity of the assay was demonstrated by a good correlation of the samples analysed by both HPLC and EIA. A kinetic profile of E-4424 in rats following an oral dose of 50 mg kg-1 has also been established.
Research Interests:
A measurement of inclusive and differential fiducial cross-sections for the production of the Higgs boson decaying into two photons is performed using $139~\text{fb}^{-1}$ of proton--proton collision data recorded at $\sqrt{s} = 13$ TeV... more
A measurement of inclusive and differential fiducial cross-sections for the production of the Higgs boson decaying into two photons is performed using $139~\text{fb}^{-1}$ of proton--proton collision data recorded at $\sqrt{s} = 13$ TeV by the ATLAS experiment at the Large Hadron Collider. The inclusive cross-section times branching ratio, in a fiducial region closely matching the experimental selection, is measured to be $67\pm 6$ fb, which is in agreement with the state-of-the-art Standard Model prediction of $64\pm 4$ fb. Extrapolating this result to the full phase space and correcting for the branching ratio, the total cross-section for Higgs boson production is estimated to be $58\pm 6$ pb. In addition, the cross-sections in four fiducial regions sensitive to various Higgs boson production modes and differential cross-sections as a function of either one or two of several observables are measured. All the measurements are found to be in agreement with the Standard Model predict...
Research Interests:
The receiver at the optical-to-thermo-hydraulic interface of a Solar Tower plant needs careful optimization in the design stage to guarantee maximum yield during operation. Due to the highly transient behavior of a Solar Tower plant,... more
The receiver at the optical-to-thermo-hydraulic interface of a Solar Tower plant needs careful optimization in the design stage to guarantee maximum yield during operation. Due to the highly transient behavior of a Solar Tower plant, evaluation of the receiver performance based on annual yield as a figure of merit is important. In this study, a novel method for the optimization of Solar Tower molten salt cavity receivers is introduced, which integrates optical, thermal, hydraulic and operational aspects. The receiver geometry, the hydraulic layout and the aiming strategy are optimized simultaneously. The optimization objective function is based on a validated simulation model that integrates a sky discretization approach for optical assessment and an Artificial Neural Network for fast system simulation. This approach allows to accelerate the transient annual assessment such that annual thermal yield can be used as figure of merit in the iterative optimization. For the latter, an Evo...