Considering the pollution and the resistance generated by chemical insecticides in Anopheles gamb... more Considering the pollution and the resistance generated by chemical insecticides in Anopheles gambiae S.L., alternative control approaches have led in this study. Larvicidal activities of the leaves of Lantana camara, Bougainvillea spectabilis and Tephrosia villosa against the fourth instar larvae of Anopheles gambiae S.L. were evaluated. The susceptibility level and the homogeneity of wild strains were determined according to the method of Sinègre. The highest mortality rates were obtained from 15mg/ml with Lantana camara and Bougainvillea spectabilis. The larvicidal activity of Lantana camara on the wild strains was higher than Bougainvillea spectabilis. These wild strains have the same sensitivity as well as the KISUMU strain towards Bougainvillea spectabilis and Lantana camara. However, the wild population response to aqueous extracts was homogeneous against Bougainvillea spectabilis and heterogeneous against Lantana camara. Lantana camara and Bougainvillea spectabilis leaves were the most active aqueous extract on larvae of Anopheles gambiae S.L.
In this study, antioxidant activity of methanol extract of stem bark of Spondias mombin (MESPM) w... more In this study, antioxidant activity of methanol extract of stem bark of Spondias mombin (MESPM) was investigated using carbon tetrachloride (CCl 4)-intoxicated rat liver as the experimental model. The intoxicated rats were administered MESPM for 14 days (daily, orally at the dose of 200 mg/kg and 400 mg/kg body weight) and silymarin at the dose of 50 mg/kg body weight. In vivo antioxidant activities of SPMME have been evaluated by using a range of methods such as measurement of lipid peroxidation by thiobarbituric acid reactive substances (TBARS), 2, 2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and ferric reducing antioxidant of plasma (FRAP) assay. Oral administration of MESPM and reference drug silymarin in intoxicated rats reduced significantly TBARS level in both serum and liver tissues and also increased significantly FRAP values and percentage inhibition of DPPH radical compared to CCl 4 group. At the dose of 400 mg/kg body weight, MESPM restored significantly of...
Considering the pollution and the resistance generated by chemical insecticides in Anopheles gamb... more Considering the pollution and the resistance generated by chemical insecticides in Anopheles gambiae S.L., alternative control approaches have led in this study. Larvicidal activities of the leaves of Lantana camara, Bougainvillea spectabilis and Tephrosia villosa against the fourth instar larvae of Anopheles gambiae S.L. were evaluated. The susceptibility level and the homogeneity of wild strains were determined according to the method of Sinègre. The highest mortality rates were obtained from 15mg/ml with Lantana camara and Bougainvillea spectabilis. The larvicidal activity of Lantana camara on the wild strains was higher than Bougainvillea spectabilis. These wild strains have the same sensitivity as well as the KISUMU strain towards Bougainvillea spectabilis and Lantana camara. However, the wild population response to aqueous extracts was homogeneous against Bougainvillea spectabilis and heterogeneous against Lantana camara. Lantana camara and Bougainvillea spectabilis leaves were the most active aqueous extract on larvae of Anopheles gambiae S.L.
In this study, antioxidant activity of methanol extract of stem bark of Spondias mombin (MESPM) w... more In this study, antioxidant activity of methanol extract of stem bark of Spondias mombin (MESPM) was investigated using carbon tetrachloride (CCl 4)-intoxicated rat liver as the experimental model. The intoxicated rats were administered MESPM for 14 days (daily, orally at the dose of 200 mg/kg and 400 mg/kg body weight) and silymarin at the dose of 50 mg/kg body weight. In vivo antioxidant activities of SPMME have been evaluated by using a range of methods such as measurement of lipid peroxidation by thiobarbituric acid reactive substances (TBARS), 2, 2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and ferric reducing antioxidant of plasma (FRAP) assay. Oral administration of MESPM and reference drug silymarin in intoxicated rats reduced significantly TBARS level in both serum and liver tissues and also increased significantly FRAP values and percentage inhibition of DPPH radical compared to CCl 4 group. At the dose of 400 mg/kg body weight, MESPM restored significantly of...
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Papers by J. Nguessan