The widely used intense pulse light (IPL) technology was first commercially launched to the medic... more The widely used intense pulse light (IPL) technology was first commercially launched to the medical market in 1994 and similar to lasers, is based on the basic principle of selective photothermolysis. The main conflict during treatments with light-based technologies is between safety and efficacy of the treatment. The aim of this study was to evaluate new IPL technology, which integrates three different pulse configurations, with specific attention on the safety and efficacy of the treatment. 101 volunteers (with Fitzpatrick skin types I-VI) were treated as follows: 9 patients underwent 8 bi-weekly acne clearance treatments, 51 patients underwent 6-12 hair removal treatments, 11 patients were treated for general skin rejuvenation, 15 patients were treated for pigmentation lesions, and 15 patients were treated for vascular lesions. No serious adverse events were recorded. All patients that were treated for hair removal achieved significant hair clearance. The patients with facial rosacea responded the fastest to the treatment. Eight of nine patients that were treated for acne clearance achieved significant reduction in acne appearance. The results represented in this study support the approach that when taking into consideration both efficacy of the treatment and safety of the patients, the system should be "flexible" enough to allow exact treatment settings profile for each patient, according to their skin type and the symptom's biophysical characteristics. <
Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency te... more Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency technology
Information on the safety of energy-based dermatological surgical devices in domestic pigs, and f... more Information on the safety of energy-based dermatological surgical devices in domestic pigs, and fractional radiofrequency (RF) devices in particular, is very limited. The aim of this study was to evaluate in a GLP-compliant study in domestic pigs the local reaction and performance of a novel fractional RF device. Five female domestic pigs were subjected to fractional RF pulses, using different energy and pulse durations and depth of penetration of the pulses. The animals were evaluated clinically and histologically at different time points (days 0, 1, 3, 7, and 14) postenergy exposure. There were no microscopic or macroscopic local adverse effects in any tested power settings, and there was time-related progressive healing, reaching complete macroscopic and microscopic healing by 7 days postapplication. As expected, there was power-related progressive increase in the incidence of ablation (destruction of skin tissue by vaporization) and coagulative necrosis of the dermis from low to...
Supplemental Material, sj-docx-1-tpx-10.1177_0192623320922958 for Local Tolerability and Performa... more Supplemental Material, sj-docx-1-tpx-10.1177_0192623320922958 for Local Tolerability and Performance Evaluation in Domestic Pigs of a Fractional Radiofrequency Device for Dermatologic Treatment by Yuval Ramot, Guy Klaiman, Michal Steiner, Yossi Lavie, Inna Belenky and Abraham Nyska in Toxicologic Pathology
... David M. Chipman a , Corresponding Author Contact Information , E-mail The Corresponding Auth... more ... David M. Chipman a , Corresponding Author Contact Information , E-mail The Corresponding Author , Ze'ev Barak a , Boaz Shaanan a , Maria Vyazmensky a , Elad Binshtein a , Inna Belenky a , Vered Temam a , Andrea Steinmetz b , 1 , Ralph Golbik b and Kai Tittmann b , 1. ...
Supplemental Material, Supp_Tables_06042020 for Local Tolerability and Performance Evaluation in ... more Supplemental Material, Supp_Tables_06042020 for Local Tolerability and Performance Evaluation in Domestic Pigs of a Fractional Radiofrequency Device for Dermatologic Treatment by Yuval Ramot, Guy Klaiman, Michal Steiner, Yossi Lavie, Inna Belenky and Abraham Nyska in Toxicologic Pathology
Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency te... more Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency technology
The widely used intense pulse light (IPL) technology was first commercially launched to the medic... more The widely used intense pulse light (IPL) technology was first commercially launched to the medical market in 1994 and similar to lasers, is based on the basic principle of selective photothermolysis. The main conflict during treatments with light-based technologies is between safety and efficacy of the treatment. The aim of this study was to evaluate new IPL technology, which integrates three different pulse configurations, with specific attention on the safety and efficacy of the treatment. 101 volunteers (with Fitzpatrick skin types I-VI) were treated as follows: 9 patients underwent 8 bi-weekly acne clearance treatments, 51 patients underwent 6-12 hair removal treatments, 11 patients were treated for general skin rejuvenation, 15 patients were treated for pigmentation lesions, and 15 patients were treated for vascular lesions. No serious adverse events were recorded. All patients that were treated for hair removal achieved significant hair clearance. The patients with facial ros...
The large, catalytic subunits (LSUs; ilvB, ilvG and ilvI, respectively) of enterobacterial acetoh... more The large, catalytic subunits (LSUs; ilvB, ilvG and ilvI, respectively) of enterobacterial acetohydroxyacid synthases isozymes (AHAS I, II and III) have molecular weights 60 kDa and are paralogous with a family of other thiamin diphosphate dependent enzymes. The small, regulatory subunits ...
Основное ограничение использования фракционных RF-систем первого поколения – невозможность создан... more Основное ограничение использования фракционных RF-систем первого поколения – невозможность создания коагуляции/некроза без абляции эпидермального слоя или наоборот – возможность абляции эпидермиса, но без коагуляции/некроза. Представлена технология Viora SVC™ второго поколения фракционных RF-систем. Тридцать добровольцев прошли курс из 3–6 процедур с применением фракционной RF-насадки аппарата V-touch. У 29 человек из 30 отмечалась заметная коррекция возрастных изменений, без осложнений и явных побочных эффектов. Благодаря широкому выбору параметров и уникальным свойствам, применение технологии SVC™ вызывает различные реакции в разных слоях кожи. Фракционная RF-манипула – RF-устройство нового поколения с расширенным контролем параметров, которое обеспечивает повышение эффективности и безопасности процедуры, а также устраняет дискомфорт во время ее проведения.
The widely used intense pulse light (IPL) technology was first commercially launched to the medic... more The widely used intense pulse light (IPL) technology was first commercially launched to the medical market in 1994 and similar to lasers, is based on the basic principle of selective photothermolysis. The main conflict during treatments with light-based technologies is between safety and efficacy of the treatment. The aim of this study was to evaluate new IPL technology, which integrates three different pulse configurations, with specific attention on the safety and efficacy of the treatment. 101 volunteers (with Fitzpatrick skin types I-VI) were treated as follows: 9 patients underwent 8 bi-weekly acne clearance treatments, 51 patients underwent 6-12 hair removal treatments, 11 patients were treated for general skin rejuvenation, 15 patients were treated for pigmentation lesions, and 15 patients were treated for vascular lesions. No serious adverse events were recorded. All patients that were treated for hair removal achieved significant hair clearance. The patients with facial ros...
Introduction: Since the introduction of fractional technology, various systems were launched to t... more Introduction: Since the introduction of fractional technology, various systems were launched to the market. The first generation of fractional RF systems created epidermal ablation with coagulative/necrosis of the dermis with sufficient clinical outcomes, but with some limitations. The aim of this study was to evaluate the efficacy and safety of SVC technology, based on the principle of separate biological responses. Material and methods: Fifty-two patients were treated for 3-6 sessions using fractional RF handpiece and eight patients received combination treatments with non-invasive RF handpiece. Results: All volunteers showed notable to significant improvement in the photoageing symptoms, without any significant complications or adverse events. Discussion: Due to its wide spectrum of parameters, the SVC technology can promote different biological responses. Owing to the &amp;amp;amp;amp;quot;Switching&amp;amp;amp;amp;quot; technology, the control of energy depth penetration enables delivery of the necessary thermal dose to the targeted skin layer. In addition, this novel technology includes the &amp;amp;amp;amp;quot;Vacuum&amp;amp;amp;amp;quot; and &amp;amp;amp;amp;quot;Cooling&amp;amp;amp;amp;quot; mechanisms, each contributing to the safety of the treatment. The Smart Heat function reduces the necessary energy levels and thereby reduces the pain level and risks for side effects.
The widely used intense pulse light (IPL) technology was first commercially launched to the medic... more The widely used intense pulse light (IPL) technology was first commercially launched to the medical market in 1994 and similar to lasers, is based on the basic principle of selective photothermolysis. The main conflict during treatments with light-based technologies is between safety and efficacy of the treatment. The aim of this study was to evaluate new IPL technology, which integrates three different pulse configurations, with specific attention on the safety and efficacy of the treatment. 101 volunteers (with Fitzpatrick skin types I-VI) were treated as follows: 9 patients underwent 8 bi-weekly acne clearance treatments, 51 patients underwent 6-12 hair removal treatments, 11 patients were treated for general skin rejuvenation, 15 patients were treated for pigmentation lesions, and 15 patients were treated for vascular lesions. No serious adverse events were recorded. All patients that were treated for hair removal achieved significant hair clearance. The patients with facial rosacea responded the fastest to the treatment. Eight of nine patients that were treated for acne clearance achieved significant reduction in acne appearance. The results represented in this study support the approach that when taking into consideration both efficacy of the treatment and safety of the patients, the system should be "flexible" enough to allow exact treatment settings profile for each patient, according to their skin type and the symptom's biophysical characteristics. <
Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency te... more Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency technology
Information on the safety of energy-based dermatological surgical devices in domestic pigs, and f... more Information on the safety of energy-based dermatological surgical devices in domestic pigs, and fractional radiofrequency (RF) devices in particular, is very limited. The aim of this study was to evaluate in a GLP-compliant study in domestic pigs the local reaction and performance of a novel fractional RF device. Five female domestic pigs were subjected to fractional RF pulses, using different energy and pulse durations and depth of penetration of the pulses. The animals were evaluated clinically and histologically at different time points (days 0, 1, 3, 7, and 14) postenergy exposure. There were no microscopic or macroscopic local adverse effects in any tested power settings, and there was time-related progressive healing, reaching complete macroscopic and microscopic healing by 7 days postapplication. As expected, there was power-related progressive increase in the incidence of ablation (destruction of skin tissue by vaporization) and coagulative necrosis of the dermis from low to...
Supplemental Material, sj-docx-1-tpx-10.1177_0192623320922958 for Local Tolerability and Performa... more Supplemental Material, sj-docx-1-tpx-10.1177_0192623320922958 for Local Tolerability and Performance Evaluation in Domestic Pigs of a Fractional Radiofrequency Device for Dermatologic Treatment by Yuval Ramot, Guy Klaiman, Michal Steiner, Yossi Lavie, Inna Belenky and Abraham Nyska in Toxicologic Pathology
... David M. Chipman a , Corresponding Author Contact Information , E-mail The Corresponding Auth... more ... David M. Chipman a , Corresponding Author Contact Information , E-mail The Corresponding Author , Ze'ev Barak a , Boaz Shaanan a , Maria Vyazmensky a , Elad Binshtein a , Inna Belenky a , Vered Temam a , Andrea Steinmetz b , 1 , Ralph Golbik b and Kai Tittmann b , 1. ...
Supplemental Material, Supp_Tables_06042020 for Local Tolerability and Performance Evaluation in ... more Supplemental Material, Supp_Tables_06042020 for Local Tolerability and Performance Evaluation in Domestic Pigs of a Fractional Radiofrequency Device for Dermatologic Treatment by Yuval Ramot, Guy Klaiman, Michal Steiner, Yossi Lavie, Inna Belenky and Abraham Nyska in Toxicologic Pathology
Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency te... more Multi-channeling optimized radiofrequency energy: A new age in well-established radiofrequency technology
The widely used intense pulse light (IPL) technology was first commercially launched to the medic... more The widely used intense pulse light (IPL) technology was first commercially launched to the medical market in 1994 and similar to lasers, is based on the basic principle of selective photothermolysis. The main conflict during treatments with light-based technologies is between safety and efficacy of the treatment. The aim of this study was to evaluate new IPL technology, which integrates three different pulse configurations, with specific attention on the safety and efficacy of the treatment. 101 volunteers (with Fitzpatrick skin types I-VI) were treated as follows: 9 patients underwent 8 bi-weekly acne clearance treatments, 51 patients underwent 6-12 hair removal treatments, 11 patients were treated for general skin rejuvenation, 15 patients were treated for pigmentation lesions, and 15 patients were treated for vascular lesions. No serious adverse events were recorded. All patients that were treated for hair removal achieved significant hair clearance. The patients with facial ros...
The large, catalytic subunits (LSUs; ilvB, ilvG and ilvI, respectively) of enterobacterial acetoh... more The large, catalytic subunits (LSUs; ilvB, ilvG and ilvI, respectively) of enterobacterial acetohydroxyacid synthases isozymes (AHAS I, II and III) have molecular weights 60 kDa and are paralogous with a family of other thiamin diphosphate dependent enzymes. The small, regulatory subunits ...
Основное ограничение использования фракционных RF-систем первого поколения – невозможность создан... more Основное ограничение использования фракционных RF-систем первого поколения – невозможность создания коагуляции/некроза без абляции эпидермального слоя или наоборот – возможность абляции эпидермиса, но без коагуляции/некроза. Представлена технология Viora SVC™ второго поколения фракционных RF-систем. Тридцать добровольцев прошли курс из 3–6 процедур с применением фракционной RF-насадки аппарата V-touch. У 29 человек из 30 отмечалась заметная коррекция возрастных изменений, без осложнений и явных побочных эффектов. Благодаря широкому выбору параметров и уникальным свойствам, применение технологии SVC™ вызывает различные реакции в разных слоях кожи. Фракционная RF-манипула – RF-устройство нового поколения с расширенным контролем параметров, которое обеспечивает повышение эффективности и безопасности процедуры, а также устраняет дискомфорт во время ее проведения.
The widely used intense pulse light (IPL) technology was first commercially launched to the medic... more The widely used intense pulse light (IPL) technology was first commercially launched to the medical market in 1994 and similar to lasers, is based on the basic principle of selective photothermolysis. The main conflict during treatments with light-based technologies is between safety and efficacy of the treatment. The aim of this study was to evaluate new IPL technology, which integrates three different pulse configurations, with specific attention on the safety and efficacy of the treatment. 101 volunteers (with Fitzpatrick skin types I-VI) were treated as follows: 9 patients underwent 8 bi-weekly acne clearance treatments, 51 patients underwent 6-12 hair removal treatments, 11 patients were treated for general skin rejuvenation, 15 patients were treated for pigmentation lesions, and 15 patients were treated for vascular lesions. No serious adverse events were recorded. All patients that were treated for hair removal achieved significant hair clearance. The patients with facial ros...
Introduction: Since the introduction of fractional technology, various systems were launched to t... more Introduction: Since the introduction of fractional technology, various systems were launched to the market. The first generation of fractional RF systems created epidermal ablation with coagulative/necrosis of the dermis with sufficient clinical outcomes, but with some limitations. The aim of this study was to evaluate the efficacy and safety of SVC technology, based on the principle of separate biological responses. Material and methods: Fifty-two patients were treated for 3-6 sessions using fractional RF handpiece and eight patients received combination treatments with non-invasive RF handpiece. Results: All volunteers showed notable to significant improvement in the photoageing symptoms, without any significant complications or adverse events. Discussion: Due to its wide spectrum of parameters, the SVC technology can promote different biological responses. Owing to the &amp;amp;amp;amp;quot;Switching&amp;amp;amp;amp;quot; technology, the control of energy depth penetration enables delivery of the necessary thermal dose to the targeted skin layer. In addition, this novel technology includes the &amp;amp;amp;amp;quot;Vacuum&amp;amp;amp;amp;quot; and &amp;amp;amp;amp;quot;Cooling&amp;amp;amp;amp;quot; mechanisms, each contributing to the safety of the treatment. The Smart Heat function reduces the necessary energy levels and thereby reduces the pain level and risks for side effects.
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