Papers by Iguatemy L O Brunetti
Bookmarks Related papers MentionsView impact
Phytochemistry, 2008
Bookmarks Related papers MentionsView impact
Photochemistry and Photobiology, 1983
Bookmarks Related papers MentionsView impact
Fitoterapia, 2006
Bookmarks Related papers MentionsView impact
Revista Brasileira de Ciências Farmacêuticas, 2007
Bookmarks Related papers MentionsView impact
Biopharmaceutics & Drug Disposition, 2012
Bookmarks Related papers MentionsView impact
BMC Nephrology, 2015
Bookmarks Related papers MentionsView impact
Latin American Journal of Pharmacy, 2008
Bookmarks Related papers MentionsView impact
Rev Cienc Farm, 1998
Bookmarks Related papers MentionsView impact
European Journal of Dentistry, 2011
Objectives:The aim of this study was to assess a suggested association between periodontitis and ... more Objectives:The aim of this study was to assess a suggested association between periodontitis and renal insufficiency by assaying kidney disease markers.Methods:Variables used to diagnose periodontitis were: (i) probing pocket depth (PPD), (ii) attachment loss (AL), (iii) bleeding on probing (BOP), (iv) plaque index (PI) and (v) extent and severity index. Blood and urine were collected from 60 apparently healthy non-smokers (men and women), consisting of a test group of 30 subjects with periodontitis (age 46±6 yrs) and a control group of 30 healthy subjects (age 43±5 yrs). Kidney function markers (urea, creatinine, uric acid and albumin contents) were measured in the serum and urine. Also, the glomerular filtration rate was estimated from creatinine clearance, from the abbreviated Modification of Diet in Renal Disease formula and from the albumin : creatinine ratio in a 24–h sample of urine.Results:It was found that the control group had a greater mean number of teeth than the test group and that the two groups also differed in PPD, AL, BOP and PI, all these variables being higher in the test group (P=0.006). For the extent and severity index of both PPD and AL, the test group had much higher medians of both extent and severity than the control group (P=0.001). With regard to kidney function, none of the markers revealed a significant difference between the control and test groups and all measured values fell within the reference intervals.Conclusions:It is proposed that severe periodontitis is not associated with any alteration in kidney function.
Bookmarks Related papers MentionsView impact
Rev Cienc Farm, 1994
Bookmarks Related papers MentionsView impact
Rev Cienc Farm, 1998
Bookmarks Related papers MentionsView impact
Rev Bras Farmacogn, 2008
Bookmarks Related papers MentionsView impact
Pharmaceutical Biology, 2006
... glucose and polyuria (Anon, 1968; Kohli & Singh, 1985; Achrekar et al., 1991; Grover et a... more ... glucose and polyuria (Anon, 1968; Kohli & Singh, 1985; Achrekar et al., 1991; Grover et al., 20012002; Vikrant et al ... Kar A, Choudhary BK, Bandyopadhyay NG (2003): Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. ...
Bookmarks Related papers MentionsView impact
Revista Da Associacao Medica Brasileira, Dec 1, 2008
Bookmarks Related papers MentionsView impact
Jornal De Pediatria, 2008
OBJETIVO: Determinar, entre um grupo de crianças e adolescentes eutróficos, os valores de glicemi... more OBJETIVO: Determinar, entre um grupo de crianças e adolescentes eutróficos, os valores de glicemia e insulinemia de jejum e de índice homeostasis model assessment (HOMA). MÉTODOS: Estudo de corte transversal realizado em duas escolas públicas de Ribeirão ...
Bookmarks Related papers MentionsView impact
ABSTRACT
Bookmarks Related papers MentionsView impact
Rev Bras Anal Clin, 1994
... 1 / 1, ADOLEC, seleciona. para imprimir. Fotocópia. Rego, Eduardo Magalhäes. Cilento, Giusepp... more ... 1 / 1, ADOLEC, seleciona. para imprimir. Fotocópia. Rego, Eduardo Magalhäes. Cilento, Giuseppe. Id: 136403. Autor: Fonseca, Luiz Marcos da; Brunetti, Iguatemy Lourenço; Rego, Eduardo Magalhaes; Garcia, Aglair Bergamo; Cilento, Giuseppe; Falcao, Roberto Passeto. ...
Bookmarks Related papers MentionsView impact
Rev Assoc Med Bras, 2009
Bookmarks Related papers MentionsView impact
BMC Nephrology, 2015
In view of the prevalence of oxidative stress in chronic kidney disease (CKD) patients, the loss ... more In view of the prevalence of oxidative stress in chronic kidney disease (CKD) patients, the loss of low-molecular-weight biomolecules by hemodialysis and the antioxidant potential of some uremic solutes that accumulate in CKD, we used in vitro model systems to test the antioxidant potential of the following uremic solutes: uric acid, hippuric acid, p-cresol, phenol, methylguanidine, L-arginine, L-tyrosine, creatinine and urea. The in vitro antioxidant efficiencies of the uremic solutes, isolated or in mixtures, were tested with the following assays: i) ABTS radical cation decolorization assay; ii) hypochlorous acid (HOCl/OCl(-)) scavenging activity; iii) superoxide anion radical (O2(•-)) scavenging activity; iv) crocin bleaching assay (capture of peroxyl radical, ROO(•)); v) hydrogen peroxide (H2O2) scavenging activity. Four of the tested uremic solutes (p-cresol, phenol, L-tyrosine, uric acid) were effective antioxidants and their IC50 were found in three model systems: ABTS(•+), HOCl/OCl(-) and crocin bleaching assay. In the 4-solutes mixtures, each one of the solute captured 12.5% for the IC50 of the mixture to ABTS(•+) or HOCl/OCl(-), exhibiting a virtually exact additive effect. In the 2-solutes mixtures, for ROO(•) capture, it was observed the need of more mass of uremic solutes to reach an IC50 value that was higher than the projected IC50, obtained from the IC50 of single solutes (25% of each, in the binary mixtures) in the same assay. In model systems for O2(•-) and H2O2, none of the uremic solutes showed scavenging activity. The use of the IC50 as an analytical tool to prepare and analyze mixtures allows the determination of their scavenging capacities and may be useful for the assessment of the antioxidant status of biological samples under conditions of altered levels of the endogenous antioxidant network and/or in the employment and monitoring of exogenous antioxidant therapy.
Bookmarks Related papers MentionsView impact
Uploads
Papers by Iguatemy L O Brunetti