... 142 REEDER, ODELL, SIODA, AND KOSKI Welch (7), Gladney (8), and Marshall (9) have presented methods of leastsquares approximation which are applicable to ... This function is normally a symmetric "bellshaped" function such... more
... 142 REEDER, ODELL, SIODA, AND KOSKI Welch (7), Gladney (8), and Marshall (9) have presented methods of leastsquares approximation which are applicable to ... This function is normally a symmetric "bellshaped" function such as the Gaussian, Lorentzian, or Voigt functions. ...
Research Interests:
All insects possess homologous segments, but segment specification differs radically among insect orders. In Drosophila, maternal morphogens control the patterned activation of gap genes, which encode transcriptional regulators that shape... more
All insects possess homologous segments, but segment specification differs radically among insect orders. In Drosophila, maternal morphogens control the patterned activation of gap genes, which encode transcriptional regulators that shape the patterned expression of pair-rule genes. This patterning cascade takes place before cellularization. Pair-rule gene products subsequently 'imprint' segment polarity genes with reiterated patterns, thus defining the primordial segments. This mechanism must be greatly modified in insect groups in which many segments emerge only after cellularization. In beetles and parasitic wasps, for instance, pair-rule homologues are expressed in patterns consistent with roles during segmentation, but these patterns emerge within cellular fields. In contrast, although in locusts pair-rule homologues may not control segmentation, some segment polarity genes and their interactions are conserved. Perhaps segmentation is modular, with each module autonomou...
Research Interests:
We studied cyclic reorganizations of filamentous actin, myosin II and microtubules in syncytial Drosophila blastoderms using drug treatments, time-lapse movies and laser scanning confocal microscopy of fixed stained embryos (including... more
We studied cyclic reorganizations of filamentous actin, myosin II and microtubules in syncytial Drosophila blastoderms using drug treatments, time-lapse movies and laser scanning confocal microscopy of fixed stained embryos (including multiprobe three-dimensional reconstructions). Our observations imply interactions between microtubules and the actomyosin cytoskeleton. They provide evidence that filamentous actin and cytoplasmic myosin II are transported along microtubules towards microtubule plus ends, with actin and myosin exhibiting different affinities for the cell's cortex. Our studies further reveal that cell cycle phase modulates the amounts of both polymerized actin and myosin II associated with the cortex. We analogize pseudocleavage furrow formation in the Drosophila blastoderm with how the mitotic apparatus positions the cleavage furrow for standard cytokinesis, and relate our findings to polar relaxation/global contraction mechanisms for furrow formation.
Research Interests: Cell Cycle, Fluorescent Dyes and Reagents, Confocal Microscopy, Development, Cytoskeleton, and 15 moreBiological Sciences, Drosophila, Mitosis, Video microscopy, Animals, Paclitaxel, Microtubules, Laser Scanning Confocal Microscopy, Kinesin, Phase Modulation, Three dimensional Reconstruction, Embryos, Drug treatment, Giant Cells, and Cycloheximide
... 39 Vol. 3I2. B Page 10. 496 GM ODELL AND JT BONNER (a) (b) (c) ... When the slime sheath plays the role of the prison walls, it may be unable to withstand this force. Then this force could 'roll out' the slime sheath at the... more
... 39 Vol. 3I2. B Page 10. 496 GM ODELL AND JT BONNER (a) (b) (c) ... When the slime sheath plays the role of the prison walls, it may be unable to withstand this force. Then this force could 'roll out' the slime sheath at the tip. In ? ... 39-2 Page 12. 498 GM O DELL AND JT BONNER ...
Research Interests:
Research Interests:
... 624 VE Foe and GM Odell ... which is quite unlike the metachronous mitotic pattern observed for cycles 10-13 (Poulson, 1950; Sonnenblick, 1950; Madhavan and Schneiderman, 1977; Turner and Mahowald, 1977; Foe and Alberts, 1983;... more
... 624 VE Foe and GM Odell ... which is quite unlike the metachronous mitotic pattern observed for cycles 10-13 (Poulson, 1950; Sonnenblick, 1950; Madhavan and Schneiderman, 1977; Turner and Mahowald, 1977; Foe and Alberts, 1983; Hartenstein and Campos-Ortega, 1985). ...