Chondroid lipoma (CL) is a rare soft tissue tumor that usually occurs in middle-aged adults and i... more Chondroid lipoma (CL) is a rare soft tissue tumor that usually occurs in middle-aged adults and is slightly more common in women. It is characterized by well-circumscribed groups of mature adipocytes of fatty tissue associated with islands of the chondromyxoid matrix but not mature chondrocytes. Clinically, CL appears as a slowly growing, painless mass in the extremities, especially the back and neck. CL must be distinguished from chondrolipoma (CLP), another benign lipoma characterized by mature adipocytes and chondrocytes. Immunohistochemistry (IHC) studies are often positive for S-100 protein and vimentin and are useful in differentiating CL from other tumors with similar histomorphology. The presence of mixed lipomatous and chondroid matrix tissue makes CL a challenging diagnosis and can be misdiagnosed as other benign or malignant tumors, and the patient does not receive the appropriate management. Although benign, an accurate diagnosis and successful surgery are required to prevent recurrence and ensure the patient has a good outcome. We present the case of a 31-year-old woman who presented with a large left shoulder soft tissue mass. The mass was suspicious for sarcoma, but with the appropriate use of IHC and molecular studies, the diagnosis of chondroid lipoma was rendered, and the patient received the proper treatment.
Microglandular adenosis (MGA) is a benign breast tumor, but it is considered a non-obligate precu... more Microglandular adenosis (MGA) is a benign breast tumor, but it is considered a non-obligate precursor to invasive breast carcinoma. MGA has a few different morphological variations, including microglandular adenosis (MGA), atypical microglandular adenosis (AMGA), and breast carcinoma-associated microglandular adenosis (BCMGA). Initially, with the identification of MGA, it was classified as a benign lesion; however, recent molecular studies have demonstrated an association between MGA, AMGA, and BCMGA. As a precancerous tumor, a definitive diagnosis of MGA is essential, including reporting the degree of atypia if present. We present the case of a 39-year-old woman whose routine mammogram revealed an irregular density, leading to her diagnosis of AMGA. We provide a brief review of the pertinent literature, including diagnosis, differential diagnosis, molecular studies, management, and outcome of MGA.
Chondroid lipoma (CL) is a rare soft tissue tumor that usually occurs in middle-aged adults and i... more Chondroid lipoma (CL) is a rare soft tissue tumor that usually occurs in middle-aged adults and is slightly more common in women. It is characterized by well-circumscribed groups of mature adipocytes of fatty tissue associated with islands of the chondromyxoid matrix but not mature chondrocytes. Clinically, CL appears as a slowly growing, painless mass in the extremities, especially the back and neck. CL must be distinguished from chondrolipoma (CLP), another benign lipoma characterized by mature adipocytes and chondrocytes. Immunohistochemistry (IHC) studies are often positive for S-100 protein and vimentin and are useful in differentiating CL from other tumors with similar histomorphology. The presence of mixed lipomatous and chondroid matrix tissue makes CL a challenging diagnosis and can be misdiagnosed as other benign or malignant tumors, and the patient does not receive the appropriate management. Although benign, an accurate diagnosis and successful surgery are required to prevent recurrence and ensure the patient has a good outcome. We present the case of a 31-year-old woman who presented with a large left shoulder soft tissue mass. The mass was suspicious for sarcoma, but with the appropriate use of IHC and molecular studies, the diagnosis of chondroid lipoma was rendered, and the patient received the proper treatment.
Microglandular adenosis (MGA) is a benign breast tumor, but it is considered a non-obligate precu... more Microglandular adenosis (MGA) is a benign breast tumor, but it is considered a non-obligate precursor to invasive breast carcinoma. MGA has a few different morphological variations, including microglandular adenosis (MGA), atypical microglandular adenosis (AMGA), and breast carcinoma-associated microglandular adenosis (BCMGA). Initially, with the identification of MGA, it was classified as a benign lesion; however, recent molecular studies have demonstrated an association between MGA, AMGA, and BCMGA. As a precancerous tumor, a definitive diagnosis of MGA is essential, including reporting the degree of atypia if present. We present the case of a 39-year-old woman whose routine mammogram revealed an irregular density, leading to her diagnosis of AMGA. We provide a brief review of the pertinent literature, including diagnosis, differential diagnosis, molecular studies, management, and outcome of MGA.
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Papers by Benjamin Love