Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic ori... more Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic origin. AFX is a curable cutaneous disease and the diagnosis depends on knowledge of its clinical and histological features and combined immunohistochemistry markers. This study presents a case of a male patient, aged 90 years, presented with painless skin lesion in his ear. The lesion had been growing progressively for 2 months, measured ∼1.5 cm, ulcerated, fixed and firm. After a biopsy, the patient underwent a complete resection with adequate surgical margins and showed favorable evolution without complications or recurrence. The histopathological evaluation showed a poorly circumscribed ulcerated dermal nodule, mesenchymal proliferation, with pleomorphic spindle cells. There was infiltration of the deep dermis and subcutis, showing malignant features, but there was no invasion of cartilage. The immunohistochemical analysis confirmed the diagnosis of AFX.
Proceedings of the 2015 Symposium on International Symposium on Physical Design - ISPD '15, 2015
This paper presents an improved benchmark suite to jointly consider logic synthesis and physical ... more This paper presents an improved benchmark suite to jointly consider logic synthesis and physical design. Usually, benchmark circuits were provided by the physical design and the logic synthesis communities separately, according to their specific needs. The files provided for each benchmark set were restricted to the views necessary for the community. Additional specifications of design intents are necessary to express optimization goals that can be shared by logic synthesis and physical design communities, as circuits alone do not carry sufficient information to establish a benchmark with a clear optimization goal. In this paper, we describe benchmarks as a set composed of circuits, design intents (constraints), floorplan, target library and technology. Disregarding pieces of information provided for the benchmarks can change the associated criticality and affect the combined or isolated outcome of logic synthesis and physical design. The proposition of this benchmark suite brings attention to the problem of considering adequately the complete context of design intent throughout the flow
Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic ori... more Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic origin. AFX is a curable cutaneous disease and the diagnosis depends on knowledge of its clinical and histological features and combined immunohistochemistry markers. This study presents a case of a male patient, aged 90 years, presented with painless skin lesion in his ear. The lesion had been growing progressively for 2 months, measured ∼1.5 cm, ulcerated, fixed and firm. After a biopsy, the patient underwent a complete resection with adequate surgical margins and showed favorable evolution without complications or recurrence. The histopathological evaluation showed a poorly circumscribed ulcerated dermal nodule, mesenchymal proliferation, with pleomorphic spindle cells. There was infiltration of the deep dermis and subcutis, showing malignant features, but there was no invasion of cartilage. The immunohistochemical analysis confirmed the diagnosis of AFX.
Proceedings of the 2015 Symposium on International Symposium on Physical Design - ISPD '15, 2015
This paper presents an improved benchmark suite to jointly consider logic synthesis and physical ... more This paper presents an improved benchmark suite to jointly consider logic synthesis and physical design. Usually, benchmark circuits were provided by the physical design and the logic synthesis communities separately, according to their specific needs. The files provided for each benchmark set were restricted to the views necessary for the community. Additional specifications of design intents are necessary to express optimization goals that can be shared by logic synthesis and physical design communities, as circuits alone do not carry sufficient information to establish a benchmark with a clear optimization goal. In this paper, we describe benchmarks as a set composed of circuits, design intents (constraints), floorplan, target library and technology. Disregarding pieces of information provided for the benchmarks can change the associated criticality and affect the combined or isolated outcome of logic synthesis and physical design. The proposition of this benchmark suite brings attention to the problem of considering adequately the complete context of design intent throughout the flow
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