Graves' Disease (DBCOND0029058)

Identifiers

Synonyms
Grave's Disease / Graves Disease / Graves Diseases / Graves' disease / Thyrotoxicosis with diffuse goiter / Graves-Basedow disease / Autoimmune hyperthyroidism / Exophthalmic goitre / Goitre exophthalmic / Exophthalmic goiter / Goiter exophthalmic / Basedow's disease / Graves' disease (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Methimazole
A thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
Propylthiouracil
A thiourea antithyroid agent used to treat hyperthyroidism.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00001159
Natural History of Thyroid Function DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT01163565
A Prospective Randomized Equivalence Trial to Evaluate the Safety of the Ligasure in Thyroid SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT03517579
Personalized Treatment in Thyroid DisordersNo drug interventionsdiagnosticNot Availablerecruiting
NCT02973802
ATX-GD-59 in Patients With Graves Disease Not Treated With Anti-thyroid TherapyNo drug interventionstreatment1completed
NCT03941184
Spontaneous Coronary Artery Dissection (SCAD) and AutoimmunityNo drug interventionsNot AvailableNot Availablecompleted
NCT05945784
Exploring Accessible Beauty for Individuals With Upper Extremity DeficitsNo drug interventionsNot AvailableNot Availablecompleted
NCT05435547
Preoperative Corticosteroids in Autoimmune Thyroid Diseasetreatment4recruiting
NCT05713097
TSI and Its Relationship With Graves' Disease RelapseNo drug interventionsNot AvailableNot Availablecompleted
NCT06204393
To Investigate the Effect of 2019 Novel Coronavirus Infection on the Condition of Patients With HyperthyroidismNo drug interventionsNot AvailableNot Availablerecruiting
NCT02376088
Characteristics of Islet β-cell Functions in Chinese Patients With Graves' DiseaseNot AvailableNot Availablecompleted
NCT05510609
Three-dimensional Ultrasonography Thyroid Volume Measurement.No drug interventionsdiagnosticNot Availableunknown_status
NCT05964452
Efficacy of Methimazole Dosing AlgorithmNot AvailableNot Availablerecruiting
NCT05118542
Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosistreatment3completed
NCT01227499
Differential Diagnosis of STA-PSV in ThyrotoxicosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01560299
Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's PatientstreatmentNot Availablecompleted
NCT04686006
Effective Iodide Therapy for Untreated Patients With Graves' Hyperthyroidism Avoiding Thionamide Drugs With Many Side EffectsNot AvailableNot Availablecompleted
NCT01320813
Trial Comparing Complication Rates Associated With Robot-assisted Thyroidectomy to External ThyroidectomyNo drug interventionstreatmentNot Availableterminated
NCT06537141
Role of Embolization of Thyroid Arteries as a Treatment for Different Thyroid DisordersNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06309316
The Impact of Person Centred Care (PCC) in Grave's DiseaseNo drug interventionssupportive_careNot Availablerecruiting
NCT06451016
Effects of Vitamin D Supplementation on Muscle Function Among Grave's Disease PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00946296
Impact of SSKI Pre-Treatment on Blood Loss in Thyroidectomy for Graves Diseasetreatment4completed
NCT06426758
Graves' Disease Induced by Epstein-Barr Virus Lytic ReactivationNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05774535
Prospective, Observational Study on the Carotid Intima-media Thickness in Patients Undergoing Thyroid SurgeryNo drug interventionsNot AvailableNot Availablerecruiting
NCT04932135
Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of HyperthyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT03013257
HIFU vs RAI in the Relapsed Graves' DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT03009357
Clinical Application of Pulse Rate-monitoring Activity Trackers in ThyrotoxicosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00782366
Predictive Genetic Risk Assessment TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT05635266
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02798965
Prevalence of Circulating Parvovirus Genome in Recently Diagnosed Graves' Disease: a Case-control StudyNo drug interventionsbasic_scienceNot Availablecompleted
NCT05461820
Effects of Different Treatment Schemes on the Regulation and Recurrence of Graves' Diseasetreatment4recruiting
NCT02203682
Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathytreatment2unknown_status
NCT01727973
Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves' Orbitopathytreatment1 / 2completed
NCT03590080
Impact of Intravenous Methylprednisolone Treatment on Blood PressureNot AvailableNot Availablecompleted
NCT00677469
Low Doses of Cholestyramine in the Treatment of HyperthyroidismtreatmentNot Availablecompleted
NCT02190214
Thyroid Disorders in Malaysia: A Nationwide Multicentre StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06240455
Phase 2 Study to Assess Efficacy & Safety of WP1302 Prevent Relapse of MMI w/Draw in Subj. w/ Graves' dztreatment2suspended
NCT03969108
Diagnostic Accuracy Study of Indocyanine Green for Parathyroid Perfusion Assessmentother4completed
NCT04239521
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia AreataNo drug interventionsNot AvailableNot Availablecompleted
NCT02993302
Effects Of Oral Alfacalcidol On Maturation Of Dendritic Cells In Graves' Disease Patientstreatment2completed
NCT03303053
Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidismtreatment3unknown_status
NCT04080505
Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?other3completed
NCT06327828
Methimazole in Graves' Disease - Comparing the Computer-aided Treatment DigiThy Versus Usual CareNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04789993
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-upNo drug interventionsNot AvailableNot Availableunknown_status
NCT00150137
Antithyroid Drugs During Radioiodine Therapytreatment4completed
NCT06506149
A Prospective Evaluation of Microwave Ablation (MWA) in the Treatment of Relapsed Graves' DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT00796913
Remission Induction and Sustenance in Graves' Disease 2No drug interventionspreventionNot Availablecompleted
NCT01039818
Comparison of Different Doses of 131I in Severe Graves' HyperthyroidismNo drug interventionstreatment3completed
NCT06134219
Course for Brain Fatigue After Graves' Disease Controlled StudyNo drug interventionstreatmentNot Availablerecruiting
NCT02210741
Next-generation Sequencing (NGS) of Peripheral Blood Immune Repertoire in Graves' DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT03498417
Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' OrbitopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT04391439
Heart Rhythm After Intravenous Methylprednisolone AdministrationNot AvailableNot Availablecompleted
NCT06081439
Validating Immunological Markers Associated With Mental Fatigue in Graves' DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT03667157
Liver Function After Intravenous Methylprednisolone AdministrationNo drug interventionssupportive_care4completed
NCT00400465
Is the Routine Pressure Dressing After Thyroidectomy Necessary?No drug interventionstreatment4completed
NCT05678374
Exploring Immunological Markers Associated With Mental Fatigue in Graves' DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT04135573
The Relationship Between NK Cell and Graves' DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT06275373
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid DysfunctionNot AvailableNot Availablerecruiting
NCT03066076
Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathytreatment3unknown_status
NCT04682340
Analysis of BPA Concentration in Serum in Women of Reproductive Age With Autoimmune Thyroid DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02491567
DNA Methylation and Autoimmune Thyroid DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT05907668
A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' Diseasetreatment2recruiting
NCT06540469
Iodine Supplementation in Graves' HyperthyroidismtreatmentNot Availablenot_yet_recruiting
NCT00432146
Effect of Lugol's Solution in the Patients With Graves' DiseaseNot AvailableNot Availablecompleted
NCT01616108
Bupivacaine Injection of Eye Muscles to Treat Strabismustreatment2 / 3unknown_status
NCT02194920
Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft FunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT01182584
Application of Digital Infrared Thermal Imaging (DITI) in Graves' DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01885533
Post-Radioiodine Graves' Management: The PRAGMA-StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00958113
Autoimmune Thyroid Disease Genetic StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02114619
Comparative Study of Different I-131 Doses in Graves' DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT00917241
Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasonetreatment4completed
NCT00145366
rhTSH, Thyroid Size, and Radioiodine Therapy in Benign Goitertreatment2completed
NCT00004660
Randomized Study of Sequential Orbital Radiotherapy for Graves' OphthalmopathyNo drug interventionstreatmentNot Availablecompleted
NCT06357494
Assessment of Thyroid Doppler Ultrasound in Followup of Pediatric Graves' DiseaseNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02205801
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and ParathyroidectomytreatmentNot Availablecompleted
NCT02373995
Role of the Microbiome in Graves' OrbitopathyNo drug interventionstreatment1 / 2unknown_status
NCT02727738
Treatment of Graves' Hyperthyroidism With Selenium Plus MethimazoletreatmentNot Availablecompleted
NCT03535090
Coagulation After Intravenous Methylprednisolone AdministrationNot AvailableNot Availablecompleted
NCT06068179
Graves' Disease Remission Study: MycoMeth Combotreatment2 / 3recruiting
NCT00697528
Color Doppler Imaging of Orbital Venous Flow in Grave's OrbitopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00505011
Genetic Polymorphisms Associated With Cigarette Smoking and Risk of Graves' DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02713256
A Study to Evaluate the Safety and Effect of CFZ533 on Patients With Graves' DiseaseNo drug interventionstreatment2completed
NCT02620085
Thyroid Disease and Personality StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01269749
Radioactive Iodide Therapy for Pediatric Graves' DiseaseNo drug interventionstreatment2completed
NCT00150124
Block-replacement Therapy During Radioiodine Therapytreatment4completed
NCT02904330
K1-70 - A Study in Subjects With Graves' DiseaseNo drug interventionstreatment1completed
NCT01950260
Early Levothyroxine Post Radioactive Iodineprevention2 / 3completed
NCT02107794
Shared Decision Making in Graves Disease - Graves Disease (GD) ChoiceNo drug interventionsNot AvailableNot Availablecompleted
NCT00335062
TSH Receptor Antibody Heterogeneity in Children and Adolescents With Graves' DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02384668
D-vitamin And Graves' Disease; Morbidity And Relapse ReductionNo drug interventionstreatmentNot Availablecompleted
NCT01534169
Function of Regulatory T Cells Improved by Dexamethasone in Graves' Patientstreatment1completed
NCT04383795
Change of Gut Microbiome in the Treatment of Graves' DiseaseNo drug interventionsNot AvailableNot Availablecompleted