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Protein-coding gene in the species Homo sapiens
ALG3 Identifiers Aliases ALG3 , CDG1D, CDGS4, D16Ertd36e, NOT56L, Not56, CDGS6, not, alpha-1,3- mannosyltransferase, ALG3 alpha-1,3- mannosyltransferaseExternal IDs OMIM : 608750 ; MGI : 1098592 ; HomoloGene : 4228 ; GeneCards : ALG3 ; OMA :ALG3 - orthologs Wikidata
Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase is an enzyme that, in humans, is encoded by the ALG3 gene .[ 5] [ 6]
This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation .[ 6]
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