From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Activator of 90 kDa heat shock protein ATPase homolog 1 is an enzyme that in humans is encoded by the AHSA1 gene .[ 5]
AHSA1 has been shown to interact with Heat shock protein 90kDa alpha (cytosolic), member A1 .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000100591 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021037 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Entrez Gene: AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)" .
^ Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C (Dec 2002). "Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1" (PDF) . Mol. Cell . 10 (6): 1307–18. doi :10.1016/S1097-2765(02)00785-2 . PMID 12504007 .
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Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C (2002). "Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1" (PDF) . Mol. Cell . 10 (6): 1307–18. doi :10.1016/S1097-2765(02)00785-2 . PMID 12504007 .
Lotz GP, Lin H, Harst A, Obermann WM (2003). "Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone" . J. Biol. Chem . 278 (19): 17228–35. doi :10.1074/jbc.M212761200 . PMID 12604615 .
Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions" . J. Neurochem . 97 (5): 1447–55. doi :10.1111/j.1471-4159.2006.03836.x . PMC 2239266 . PMID 16696853 .
Wang X, Venable J, LaPointe P, Hutt DM, Koulov AV, Coppinger J, Gurkan C, Kellner W, Matteson J, Plutner H, Riordan JR, Kelly JW, Yates JR, Balch WE (2006). "Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis" . Cell . 127 (4): 803–15. doi :10.1016/j.cell.2006.09.043 . PMID 17110338 . S2CID 1457851 .
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