The 1972BC Lions finished in fifth place in the Western Conference with a 5–11 record and failed to make the playoffs.
After Paul Brothers was traded to Ottawa late in the 1971 season and Tom Wilkinson was released, sophomore pivot Don Moorhead became the Lions' starting quarterback. While Moorhead threw for 2606 yards, he also threw 17 interceptions and the offence continued to struggle at only 15.9 points per game.
The lone bright spot on offence was receiver Jim Young. He led the league with 1362 yards receiving and won his second Schenley as Outstanding Canadian. Young was a CFL all-star along with rookie linebacker Ray Nettles, for whom the Lions outbid the Miami Dolphins of the NFL in the off-season.
For the first season since the 1950s, the team wore orange jerseys at home. The new jerseys had northwestern stripes on each arm.