Spinetoram

Spinetoram
Clinical data
Trade names	Cheristin
ATCvet code	QP53AX31 (WHO) ;
Identifiers
	IUPAC name (2R,5R,9R,10S,14R,15S,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-7-[(2R,3R,4R,5S,6S)-4-ethoxy-3,5-dimethoxy-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-20-oxatetracyclo[10.10.0.02,10.05,9]docos-11-ene-13,21-dione;
CAS Number	935545-74-7 ;
PubChem CID	53297414;
ChemSpider	30791336;
UNII	YGZ1037ELN;
CompTox Dashboard (EPA)	DTXSID3058614 ;
ECHA InfoCard	100.211.310
Chemical and physical data
Formula	C42H69NO10
Molar mass	748.011 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1CCCC(C(C(=O)C2=CC3C(C2CC(=O)O1)CCC4C3CC(C4)OC5C(C(C(C(O5)C)OC)OCC)OC)C)OC6CCC(C(O6)C)N(C)C;
	InChI InChI=InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 ; Key:GOENIMGKWNZVDA-OAMCMWGQSA-N;

Spinetoram (marketed as Cheristin in its topical veterinary dosage-form) is an insecticidal mixture of two active neurotoxic constituents of Saccharopolyspora spinosa.^[1] It is used to control pest insects in stored grain^[2] and on domestic cats.^[3]

References

^ Bacci L, Lupi D, Savoldelli S, Rossaro B (2016-04-28). "A review of Spinosyns, a derivative of biological acting substances as a class of insecticides with a broad range of action against many insect pests". Journal of Entomological and Acarological Research. 48 (1): 40. doi:10.4081/jear.2016.5653. hdl:2434/380778. ISSN 2279-7084.
^ Vassilakos TN, Athanassiou CG, Tsiropoulos NG (2015). "Influence of grain type on the efficacy of spinetoram for the control of Rhyzopertha dominica, Sitophilus granarius and Sitophilus oryzae". Journal of Stored Products Research. 64: 1–7. doi:10.1016/j.jspr.2015.02.002.
^ Paarlberg T, Winkle J, Rumschlag AJ, Young LM, Ryan WG, Snyder DE (February 2017). "®) for cats". Parasites & Vectors. 10 (1): 59. doi:10.1186/s13071-017-1996-9. PMC 5288883. PMID 28148275.

[1] Bacci L, Lupi D, Savoldelli S, Rossaro B (2016-04-28). "A review of Spinosyns, a derivative of biological acting substances as a class of insecticides with a broad range of action against many insect pests". Journal of Entomological and Acarological Research. 48 (1): 40. doi:10.4081/jear.2016.5653. hdl:2434/380778. ISSN 2279-7084.

[2] Vassilakos TN, Athanassiou CG, Tsiropoulos NG (2015). "Influence of grain type on the efficacy of spinetoram for the control of Rhyzopertha dominica, Sitophilus granarius and Sitophilus oryzae". Journal of Stored Products Research. 64: 1–7. doi:10.1016/j.jspr.2015.02.002.

[3] Paarlberg T, Winkle J, Rumschlag AJ, Young LM, Ryan WG, Snyder DE (February 2017). "®) for cats". Parasites & Vectors. 10 (1): 59. doi:10.1186/s13071-017-1996-9. PMC 5288883. PMID 28148275.

[1]

[2]

[3]

Spinetoram

See also

References