Iomeprol

Iomeprol
Clinical data
Trade names	Imeron, Iomeron
Routes of; administration	Intravenous, by mouth
ATC code	V08AB10 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Metabolism	none
Elimination half-life	109±20 min
Excretion	via kidneys
Identifiers
	IUPAC name 1-N,3-N-bis(2,3-dihydroxypropyl)-5-(2-hydroxy-N-methylacetamido)-2,4,6-triiodobenzene-1,3-dicarboxamide;
CAS Number	78649-41-9;
PubChem CID	3731;
DrugBank	DB11705;
ChemSpider	3600;
UNII	17E17JBP8L;
KEGG	D01719;
ChEBI	CHEBI:31710 ;
CompTox Dashboard (EPA)	DTXSID1049061 ;
Chemical and physical data
Formula	C17H22I3N3O8
Molar mass	777.089 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Ic1c(c(I)c(c(I)c1N(C(=O)CO)C)C(=O)NCC(O)CO)C(=O)NCC(O)CO;
	InChI InChI=1S/C17H22I3N3O8/c1-23(9(29)6-26)15-13(19)10(16(30)21-2-7(27)4-24)12(18)11(14(15)20)17(31)22-3-8(28)5-25/h7-8,24-28H,2-6H2,1H3,(H,21,30)(H,22,31); Key:NJKDOADNQSYQEV-UHFFFAOYSA-N;

Iomeprol is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It is sold under the trade names Imeron and Iomeron.^[1]^[2]

It is classified as a water-soluble, nephrotrophic, low osmolar X-ray contrast medium.^[1] Low osmolar non-ionic agents are better tolerated and less likely to cause side effects than the high osmolar ionic agents.^[1]

The substance is not metabolized in the human body but excreted in unchanged form. It is decomposed slowly and can therefore accumulate in the environment.^[3]

References

^ ^a ^b ^c Rossiter D (2014). South African medicines formulary (11th ed.). Rondebosch, South Africa: Health and Medical Pub. Group of the South African Medical Association. ISBN 978-1-875098-30-9. OCLC 869772940.
^ Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Iomeron 300 mg J/ml-Infusionsflasche.
^ Pfundstein P, Martin C, Schulz W, Seitz W, Ruth KM, Wille A, Steinbach A, Flottmann D (January 2015). "IC-ICP/MS-Analytik". GIT Labor-Fachzeitschrift (in German): 29–31.

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

[Rossiter_2014-1] Rossiter D (2014). South African medicines formulary (11th ed.). Rondebosch, South Africa: Health and Medical Pub. Group of the South African Medical Association. ISBN 978-1-875098-30-9. OCLC 869772940.

[AC-2] Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Iomeron 300 mg J/ml-Infusionsflasche.

[3] Pfundstein P, Martin C, Schulz W, Seitz W, Ruth KM, Wille A, Steinbach A, Flottmann D (January 2015). "IC-ICP/MS-Analytik". GIT Labor-Fachzeitschrift (in German): 29–31.

[1]

[2]

[3]

Clinical data

Trade names	Imeron, Iomeron
Routes of administration	Intravenous, by mouth
ATC code	V08AB10 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Metabolism	none
Elimination half-life	109±20 min
Excretion	via kidneys
Identifiers
IUPAC name 1-N,3-N-bis(2,3-dihydroxypropyl)-5-(2-hydroxy-N-methylacetamido)-2,4,6-triiodobenzene-1,3-dicarboxamide
CAS Number	78649-41-9
PubChem CID	3731
DrugBank	DB11705
ChemSpider	3600
UNII	17E17JBP8L
KEGG	D01719
ChEBI	CHEBI:31710^Y
CompTox Dashboard (EPA)	DTXSID1049061
Chemical and physical data
Formula	C₁₇H₂₂I₃N₃O₈
Molar mass	777.089 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Ic1c(c(I)c(c(I)c1N(C(=O)CO)C)C(=O)NCC(O)CO)C(=O)NCC(O)CO
InChI InChI=1S/C17H22I3N3O8/c1-23(9(29)6-26)15-13(19)10(16(30)21-2-7(27)4-24)12(18)11(14(15)20)17(31)22-3-8(28)5-25/h7-8,24-28H,2-6H2,1H3,(H,21,30)(H,22,31) Key:NJKDOADNQSYQEV-UHFFFAOYSA-N

Iomeprol

See also

References