Cohort Profile: The Xiamen Pubertal Growth Cohort Longitudinal Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Participants
2.2. Ethical Consideration
2.3. Physical Examination
2.4. Sample Collection
2.5. Quality Control
3. Key Findings
3.1. Primary Results
3.2. Discussion
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Time | November 2017 | May 2018 | November 2018 | May 2019 | November 2019 | November 2020 | Device | Method |
---|---|---|---|---|---|---|---|---|
Measurement | ||||||||
Sample size | 2125 | 1416 | 1372 | 1370 | 1338 | 1272 | - | - |
Weight | ○ | ○ | ○ | ○ | ○ | ○ | Electronic weight scale, TANITA HD-394, Japan | Barefoot, to the nearest of 0.1 kg, measured twice |
Height | ○ | ○ | ○ | ○ | ○ | ○ | Portable stadiometer, model TZG, China | Barefoot, to the nearest of 0.1 cm, measured twice |
Waist circumference | ○ | ○ | ○ | ○ | ○ | ○ | Body measuring tape, Myotape, America | Without shirts, to the nearest of 0.1 cm located at midline of the participant’s armpit, at the midpoint between the lower part of the last rib and the top of the hip, measured twice |
Tanner stage | ○ | ○ | ○ | ○ | ○ | ○ | Tanner stage atlas and testis development model | Physical examination measured with 2 fixed staff |
Body composition | ○ | ○ | ○ | ○ | ○ | ○ | Tanita MC-180, Japan | With light clothes, barefoot, in silence |
Blood pressure | ○ | ○ | ○ | ○ | ○ | ○ | Mercury sphygmomanometer for November 2017 (XJ11D, China). Electronic monitor for follow-up (Omron HBP-1100, Japan) | With proper cuff, in silence, measured twice, with a difference within 10 mmHg |
Blood biochemical | ○ | ○ | ○ | ○ | Automatic biochemistry analyzer. Roche Cobas, Switzerland | After 12 h overnight fast. Sample was centrifuged at 3000r for 10 min, aliquoted and stored at −80 °C Morning urine sample, stored at −80 °C | ||
Urine phthalates | ○ | Standards solutions (Toronto Research Chemicals Inc.) | ||||||
Serum sex hormone | ○ | ○ | ○ | ○ | Radioimmunoassay system, XH6080, China | |||
Students’ questionnaire | ○ | ○ | ○ | ○ | Background information, habits on dietary intake, habits on physical activities, knowledge on healthy lifestyle | |||
Guardians’ questionnaire | ○ | □ | ○ | □ | ○ | ○ | Child’s birth factors, family background information, parental health status, parental habits on dietary intake, parental habits on physical activities, parental knowledge on healthy lifestyle, family history of noncommunicable chronic diseases. |
Variables | Included | Excluded | p Value |
---|---|---|---|
All | |||
Sample size, n (%) | 945 | 327 | |
Boys, n (%) | 504 (53.3) | 163 (49.8) | 0.117 |
Age, year, mean (SD) | 8.6 (0.8) | 8.4 (0.7) | <0.001 |
Height, cm, mean (SD) | 133.1 (7.2) | 131.4 (7.1) | <0.001 |
weight, kg, mean (SD) | 29.8 (8.0) | 28.3 (7.4) | 0.002 |
BMI, kg/m2, mean (SD) | 16.6 (3.0) | 16.2 (2.9) | 0.017 |
Boys | |||
ATO, year, mean (SD) | 8.2 (1.6) | 8.5 (1.5) | 0.065 |
APHV, year, mean (SD) | 11.4 (1.1) | 11.1 (1.5) | 0.007 |
Tanner II age, year, mean (SD) | 11.0 (0.8) | - | - |
Girls | |||
ATO, year, mean (SD) | 7.4 (1.0) | 7.3 (0.9) | 0.265 |
APHV, year, mean (SD) | 9.3 (1.2) | 9.1 (1.2) | 0.113 |
Tanner II age, year, mean (SD) | 9.7 (0.9) | - | - |
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Wang, X.; Li, Y.; Gao, D.; Yang, Z.; Dong, B.; Dong, Y.; Zou, Z.; Ma, J. Cohort Profile: The Xiamen Pubertal Growth Cohort Longitudinal Study. Future 2023, 1, 4-12. https://doi.org/10.3390/future1010003
Wang X, Li Y, Gao D, Yang Z, Dong B, Dong Y, Zou Z, Ma J. Cohort Profile: The Xiamen Pubertal Growth Cohort Longitudinal Study. Future. 2023; 1(1):4-12. https://doi.org/10.3390/future1010003
Chicago/Turabian StyleWang, Xijie, Yanhui Li, Di Gao, Zhaogeng Yang, Bin Dong, Yanhui Dong, Zhiyong Zou, and Jun Ma. 2023. "Cohort Profile: The Xiamen Pubertal Growth Cohort Longitudinal Study" Future 1, no. 1: 4-12. https://doi.org/10.3390/future1010003