[go: up one dir, main page]

Journal of Epidemiology
Online ISSN : 1349-9092
Print ISSN : 0917-5040
ISSN-L : 0917-5040
Study Profile
The Tohoku Medical Megabank Project: Design and Mission
Graduate School of Medicine, Tohoku University
International Research Institute of Disaster Science, Tohoku University">Shinichi Kuriyama
Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Nobuo Yaegashi
Fuji NagamiTomohiko AraiYoshio Kawaguchi Graduate School of Medicine, Tohoku University">Noriko OsumiMasaki Sakaida Graduate School of Medicine, Tohoku University">Yoichi Suzuki Graduate School of Medicine, Tohoku University">Keiko NakayamaHiroaki HashizumeGen Tamiya Graduate School of Medicine, Tohoku University">Hiroshi Kawame Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Kichiya Suzuki
Graduate School of Medicine, Tohoku University">Atsushi Hozawa Graduate School of Medicine, Tohoku University">Naoki Nakaya Graduate School of Medicine, Tohoku University">Masahiro Kikuya Graduate School of Medicine, Tohoku University">Hirohito Metoki Graduate School of Medicine, Tohoku University">Ichiro Tsuji Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Nobuo Fuse
Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Hideyasu Kiyomoto
Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Junichi Sugawara
Tohoku University Hospital, Tohoku University
Graduate School of Dentistry, Tohoku University">Akito Tsuboi
Graduate School of Medicine, Tohoku University
International Research Institute of Disaster Science, Tohoku University
Tohoku University Hospital, Tohoku University">Shinichi Egawa
Graduate School of Medicine, Tohoku University
International Research Institute of Disaster Science, Tohoku University
Tohoku University Hospital, Tohoku University">Kiyoshi Ito
Graduate School of Medicine, Tohoku University
International Research Institute of Disaster Science, Tohoku University
Tohoku University Hospital, Tohoku University">Koichi Chida
Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Tadashi Ishii
Graduate School of Medicine, Tohoku University
International Research Institute of Disaster Science, Tohoku University
Tohoku University Hospital, Tohoku University">Hiroaki Tomita
Graduate School of Medicine, Tohoku University
Institute of Development, Aging and Cancer, Tohoku University">Yasuyuki Taki
Graduate School of Medicine, Tohoku University">Naoko Minegishi Graduate School of Medicine, Tohoku University">Naoto Ishii Graduate School of Medicine, Tohoku University">Jun Yasuda Graduate School of Medicine, Tohoku University">Kazuhiko Igarashi Graduate School of Medicine, Tohoku University">Ritsuko ShimizuMasao NagasakiSeizo Koshiba Graduate School of Information Sciences, Tohoku University">Kengo KinoshitaSoichi OgishimaTakako Takai-Igarashi Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Teiji Tominaga
Graduate School of Medicine, Tohoku University">Osamu Tanabe Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Noriaki Ohuchi
Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Toru Shimosegawa
Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Shigeo Kure
Hiroshi Tanaka Graduate School of Medicine, Tohoku University
Tohoku University Hospital, Tohoku University">Sadayoshi Ito
School of Medicine, Iwate Medical University">Jiro Hitomi School of Medicine, Iwate Medical University">Kozo Tanno School of Medicine, Iwate Medical University">Motoyuki Nakamura School of Medicine, Iwate Medical University">Kuniaki Ogasawara School of Medicine, Iwate Medical University">Seiichiro Kobayashi School of Medicine, Iwate Medical University">Kiyomi Sakata School of Medicine, Iwate Medical University
Institute for Biomedical Science, Iwate Medical University">Mamoru Satoh
Atsushi Shimizu School of Medicine, Iwate Medical University
Institute for Biomedical Science, Iwate Medical University">Makoto Sasaki
School of Medicine, Iwate Medical University">Ryujin Endo School of Medicine, Iwate Medical University
Institute for Biomedical Science, Iwate Medical University">Kenji Sobue
the Tohoku Medical Megabank Project Study Group Graduate School of Medicine, Tohoku University">Masayuki Yamamoto
Author information
JOURNAL FREE ACCESS
Supplementary material

2016 Volume 26 Issue 9 Pages 493-511

Details
Abstract

The Great East Japan Earthquake (GEJE) and resulting tsunami of March 11, 2011 gave rise to devastating damage on the Pacific coast of the Tohoku region. The Tohoku Medical Megabank Project (TMM), which is being conducted by Tohoku University Tohoku Medical Megabank Organization (ToMMo) and Iwate Medical University Iwate Tohoku Medical Megabank Organization (IMM), has been launched to realize creative reconstruction and to solve medical problems in the aftermath of this disaster. We started two prospective cohort studies in Miyagi and Iwate Prefectures: a population-based adult cohort study, the TMM Community-Based Cohort Study (TMM CommCohort Study), which will recruit 80 000 participants, and a birth and three-generation cohort study, the TMM Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study), which will recruit 70 000 participants, including fetuses and their parents, siblings, grandparents, and extended family members. The TMM CommCohort Study will recruit participants from 2013 to 2016 and follow them for at least 5 years. The TMM BirThree Cohort Study will recruit participants from 2013 to 2017 and follow them for at least 4 years. For children, the ToMMo Child Health Study, which adopted a cross-sectional design, was also started in November 2012 in Miyagi Prefecture. An integrated biobank will be constructed based on the two prospective cohort studies, and ToMMo and IMM will investigate the chronic medical impacts of the GEJE. The integrated biobank of TMM consists of health and clinical information, biospecimens, and genome and omics data. The biobank aims to establish a firm basis for personalized healthcare and medicine, mainly for diseases aggravated by the GEJE in the two prefectures. Biospecimens and related information in the biobank will be distributed to the research community. TMM itself will also undertake genomic and omics research. The aims of the genomic studies are: 1) to construct an integrated biobank; 2) to return genomic research results to the participants of the cohort studies, which will lead to the implementation of personalized healthcare and medicine in the affected areas in the near future; and 3) to contribute the development of personalized healthcare and medicine worldwide. Through the activities of TMM, we will clarify how to approach prolonged healthcare problems in areas damaged by large-scale disasters and how useful genomic information is for disease prevention.

Content from these authors
© 2016 Shinichi Kuriyama et al. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Previous article
feedback
Top