We would like to correct this Letter, which demonstrated the molecular characteristics and functional nature of lymphatics serving the central nervous system (CNS), by adding two reference citations, of which we became aware after publication. Foldi et al.1 postulated a CNS–lymphatic link, although their findings described lymphatic vessels located at the base of the skull, which differs from the location of the vessels that we identified and functionally characterized. Andres et al.2 presented incidental histological evidence of dural vessels in rats that, on the basis of ultrastructural features, appeared to be lymphatic. We also wish to clarify that the designation of these lymphatics as ‘CNS lymphatics’ in our Letter refers to their function of CNS/cerebrospinal fluid drainage.
References
Földi, M. et al. New contributions to the anatomical connections of the brain and the lymphatic system. Acta Anat. 64, 498–505 (1966)
Andres, K. H., von During, M., Muszynski, K. & Schmidt, R. F. Nerve fibres and their terminals of the dura mater encephali of the rat. Anat. Embryol. 175, 289–301 (1987)
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Louveau, A., Smirnov, I., Keyes, T. et al. Correction: Corrigendum: Structural and functional features of central nervous system lymphatic vessels. Nature 533, 278 (2016). https://doi.org/10.1038/nature16999
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DOI: https://doi.org/10.1038/nature16999
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