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Long-term adherence to ambulatory initiated continuous positive airway pressure in non-syndromic OSA children

  • Sleep Breathing Physiology and Disorders • Short Communication
  • Published:
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Abstract

Purpose

In children, the usual indications for continuous positive airway pressure (CPAP) are residual OSA after adenotonsillectomy and/or persistent OSA due to obesity. Data concerning adherence (hours/night) following ambulatory CPAP initiation are scarce.

Methods

An observational cohort of 78 children was followed over 2 years. All exhibited sleep-disordered breathing (SDB) symptoms, were assessed by polysomnography, and prescribed CPAP. CPAP was initiated at hospital for 10 children.

Results

OSA children, mean age 10.4 ± 3.2 years, were mostly males (75.6%), with a mean body mass index of 21.2 ± 7.3 kg/m2, and mean apnea+hypopnea index of 12.2 ± 10.6 events/hour. Seventy-two children were still on CPAP at 3 months, 63 at 6 months, 55 at 1 year, and 34 at 2 years. CPAP was discontinued thanks to rehabilitation programs, dento-facial orthopedics, and/or weight loss. Mean CPAP adherence at 1, 3, 6, 12, and 24 months was respectively 6.1 ± 2.8, 6.2 ± 2.6, 6.2 ± 2.8, 6.3 ± 2.8, and 7.0 ± 2.7 h/night. There was a trend towards higher CPAP adherence and younger age, primary versus middle/high school attendance, higher baseline apnea+hypopnea index, and neurocognitive disorders.

Conclusion

In our population, mean CPAP adherence defined in hours per night was high and did not decrease during the 24-month follow-up. These findings support the feasibility of ambulatory CPAP initiation in non-syndromic OSA. The high CPAP adherence is expected to be associated with improvements in neurocognition, and in metabolic and cardiovascular parameters.

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Acknowledgements

The authors would like to thank Alison Foote (Grenoble Alpes University Hospital, France) for critically editing the manuscript.

Funding

This work was supported by the French National Research Agency in the framework of the “Investissements d’avenir” program (ANR-15-IDEX-02) and the E-health and Integrated Care Chair of excellence from the Grenoble Alpes University Foundation.

Author information

Authors and Affiliations

  1. Unité Veille-Sommeil, Hôpital Jean Bernard, Valenciennes, France

    M-P. Perriol

  2. Pôle Thorax et Vaisseaux, Explorations fonctionnelles cardiorespiratoires, CHU Grenoble Alpes, Grenoble, France

    I. Jullian-Desayes, M. Joyeux-Faure, S. Bailly & J-L. Pépin

  3. Laboratoire HP2, INSERM U1042, Université Grenoble Alpes, Grenoble, France

    I. Jullian-Desayes, M. Joyeux-Faure, S. Bailly & J-L. Pépin

  4. Pôle d’Exploration des Apnées du Sommeil, Nouvelle Clinique Bel air, Bordeaux, France

    A. Andrieux

  5. Private practice, Albi, France

    M. Ellaffi

  6. Hôpital Privé de La Louvière, Lille, France

    F. Jounieaux & C. Lamblin

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  1. M-P. Perriol
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  8. J-L. Pépin
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Corresponding author

Correspondence to I. Jullian-Desayes.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from both parents of all individual participants included in the study.

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Perriol, MP., Jullian-Desayes, I., Joyeux-Faure, M. et al. Long-term adherence to ambulatory initiated continuous positive airway pressure in non-syndromic OSA children. Sleep Breath 23, 575–578 (2019). https://doi.org/10.1007/s11325-018-01775-2

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  • DOI: https://doi.org/10.1007/s11325-018-01775-2

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