Abstract
The filamentous fungusTalaromyces helicus , isolated from oil-contaminated sludge, oxidizes biphenyl via 4-hydroxybiphenyl to the dihydroxylated derivatives 4,4′-dihydroxybiphenyl and 3,4-dihydroxybiphenyl, which, to a certain extent, are converted to glycosyl conjugates. The sugar moiety of the conjugate formed from 4,4′-dihydroxybiphenyl was identified as glucose. Further metabolites: 2-hydroxybiphenyl, 2,5-dihydroxylated biphenyl, and the ring cleavage product 4-phenyl-2-pyrone-6-carboxylic acid accumulated only in traces. From these results the main pathway for biotransformation of biphenyl in T. helicus could be proposed to be the excretion of dihydroxylated derivatives (>75%) and their glucosyl conjugates (<25%).
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Romero, M.C., Hammer, E., Hanschke, R. et al. Biotransformation of biphenyl by the filamentous fungus Talaromyces helicus. World J Microbiol Biotechnol 21, 101–106 (2005). https://doi.org/10.1007/s11274-004-2779-y
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DOI: https://doi.org/10.1007/s11274-004-2779-y