Abstract
The active ingredients of many Chinese medicinal plants are secondary metabolites, which exhibit pharmaceutical value. In the metabolism process of secondary metabolites, transcription factors play important roles in regulating a series of genes in the metabolic pathway, thereby regulating the direction and the speed of metabolic flow. Therefore, the intervention of transcription factor by genetic engineering is an important method to regulate secondary metabolism in Chinese medicinal plants. This article summarizes the functions and regulatory mechanism of transcription factors had been studied in secondary metabolites of Chinese medicinal plants, which will help researchers in-depth understand the metabolism network of secondary metabolites, further improve the quality of Chinese medicinal plants.
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Abbreviations
- ABA:
-
abscisic acid
- AP2/ERF:
-
APETALA2/ethylene-responsive element binding factors
- ARF:
-
auxin response factor
- bHLH:
-
basic-helix-loop-helix
- bZIP:
-
basicregion leucine-zipper proteins
- DS:
-
dammarenediol II synthase
- ICE1:
-
Inducer of CBF Expression 1
- JA:
-
jasmonic acid
- MeJA:
-
methyl jasmonate
- MYB:
-
V-myb myeloblastosis viral oncogene homolog
- RACE:
-
rapid-amplification of cDNA ends
- RT-qPCR:
-
real-time quantitative PCR
- SA:
-
salicylic acid
- SE:
-
squalene epoxidase gene
- TCM:
-
traditional Chinese medicines
- TFs:
-
transcription factors
- TIAs:
-
terpenoid indole alkaloids
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Acknowledgements
The authors would like to acknowledge the support of the Research Project Supported by Shanxi Scholarship Council of China (2020 − 132), and the Award Fund for Excellent doctoral Graduates Working in Shanxi Province (2020BKS03).
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This work was supported by the Research Project Supported by Shanxi Scholarship Council of China (2020 − 132), and the Award Fund for Excellent doctoral Graduates Working in Shanxi Province (2020BKS03).
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Yang, L., Miao, L., Gong, Q. et al. Advances in studies on transcription factors in regulation of secondary metabolites in Chinese medicinal plants. Plant Cell Tiss Organ Cult 151, 1–9 (2022). https://doi.org/10.1007/s11240-022-02334-0
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DOI: https://doi.org/10.1007/s11240-022-02334-0